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Cephalosporins - 1st Generation WHO AWaRe: Access Prescription only

Cefazolin — Compare Prices at US & Canada Pharmacies

Compare real Cefazolin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Cephalosporins - 1st Generation
Common forms
Injectable (reconstituted)
Generic available
Yes
Legal status
Prescription only

Does insurance typically cover Cefazolin in Sodium Chloride, and what would my out-of-pocket cost be?

Coverage and copay amounts for Cefazolin in Sodium Chloride depend entirely on your individual insurance plan. Formulary status, tier placement, and copay structure vary significantly between insurers and specific plans. To find out whether your plan covers this medication and what your actual copay would be, contact your insurance provider directly. If your insurance does not cover it or your copay is high, discount cards and pharmacy price-comparison tools can help reduce your cost at the point of sale.

What is the typical cost of Cefazolin in Sodium Chloride without insurance coverage?

The average retail price for Cefazolin in Sodium Chloride without health insurance is around $37.94 per 1, 2-0.9gm/100ml-% solution. Many patients find lower prices by using manufacturer coupons, pharmacy discount programs, or comparing prices across different pharmacy chains. Since Cefazolin in Sodium Chloride is a generic formulation, it is considerably less expensive than the brand-name alternatives Kefzol or Ancef.

What are the brand-name versions of Cefazolin in Sodium Chloride?

Kefzol and Ancef are the established brand-name formulations of cefazolin in sodium chloride. The generic version is substantially more affordable while containing identical active ingredients. Most patients and healthcare providers opt for the generic form to reduce medication expenses without compromising therapeutic efficacy.

Cefazolin prices at US pharmacies

Cefazolin In Sodium Chloride — solution (quantity in ml), 2-0.9gm/100ml-%, qty 100

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $29.25 $26.25
Harris Teeter Pharmacy $29.25 $26.25
Walmart Neighborhood Market $31.55 $28.55
Walmart Pharmacy $31.55 $28.55
Walgreens $32.19 $29.19
Publix $33.59 $30.59
CVS Pharmacy $35.90 $32.90

Cefazolin Sodium — solution reconstituted, 10gm, qty 2

PharmacyRetail priceWith discount card
CVS Pharmacy Lowest $6.57 $3.57
Walgreens $11.36 $8.36
Food Lion $22.02
Costco $27.05
Publix $40.18 $37.18
Kroger Pharmacy $43.20 $40.20
Harris Teeter Pharmacy $43.20 $40.20
Walmart Neighborhood Market $48.92 $45.92

Cefazolin prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Cefazolin in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Cefazolin used for?

Cefazolin in Sodium Chloride belongs to the first-generation cephalosporins class and is manufactured by Quva Pharma. This is a generic medication; brand-name equivalents include Kefzol and Ancef. Typical retail pricing runs approximately $37.94 per 1, 2-0.9gm/100ml-% solution, though discount programs and pharmacy comparison shopping may yield lower out-of-pocket costs.

Available forms

solution (quantity in ml), solution reconstituted

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

CONTRAINDICATIONS CEFAZOLIN FOR INJECTION IS CONTRAINDICATED IN PATIENTS WITH KNOWN ALLERGY TO THE CEPHALOSPORIN GROUP OF ANTIBIOTICS.

Warnings

WARNINGS BEFORE THERAPY WITH CEFAZOLIN FOR INJECTION IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEFAZOLIN, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS. IF THIS PRODUCT IS GIVEN TO PENICILLIN‑SENSITIVE PATIENTS, CAUTION SHOULD BE EXERCISED BECAUSE CROSS‑HYPERSENSITIVITY AMONG BETA‑LACTAM ANTIBIOTICS HAS BEEN CLEARLY DOCUMENTED AND MAY OCCUR IN UP TO 10% OF PATIENTS WITH A HISTORY OF PENICILLIN ALLERGY. IF AN ALLERGIC REACTION TO CEFAZOLIN FOR INJECTION OCCURS, DISCONTINUE TREATMENT WITH THE DRUG.

Known drug interactions

Drug Interactions Probenecid may decrease renal tubular secretion of cephalosporins when used concurrently, resulting in increased and more prolonged cephalosporin blood levels. Drug/Laboratory Test Interactions A false positive reaction for glucose in the urine may occur with Benedict’s solution, Fehling’s solution or with CLINITEST ® tablets, but not with enzyme-based tests such as CLINISTIX ® . Positive direct and indirect antiglobulin (Coombs) tests have occurred; these may also occur in neonates whose mothers received cephalosporins before delivery.

Pregnancy & breastfeeding

Pregnancy Teratogenic Effects: Pregnancy Category B. Reproduction studies have been performed in rats, mice, and rabbits at doses up to 25 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to Cefazolin for Injection. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Cefazolin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$4.4M
Medicare Part D spend, 2024
82.1K
Medicare Part D claims, 2024
21
FDA-listed manufacturers (Orange Book)
$14.49
Federal (VA) contract price per pack (10X100ML)

Frequently asked questions

How much does Cefazolin cost without insurance?
Retail (no-insurance) prices we found for Cefazolin range up to about $48.92 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $3.57. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Cefazolin?
Yes — our pricing data includes at least one generic listing for Cefazolin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Cefazolin in?
Cefazolin belongs to the cephalosporins - 1st generation class of antibiotics. WHO classifies it as an 'Access' antibiotic under its AWaRe stewardship framework.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.