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Polymyxins WHO AWaRe: Reserve Prescription only

Colistimethate (Coly-Mycin M) — Compare Prices at US & Canada Pharmacies

Compare real Colistimethate prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Generic name Colistimethate
Also sold as
Coly-Mycin M
Drug class
Polymyxins
Common forms
Injectable (reconstituted)
Generic available
Yes
Legal status
Prescription only

What is the typical out-of-pocket cost of Colistimethate Sodium (Cba)?

Without insurance, the average retail price for Colistimethate Sodium (Cba) is $1,306.36 per 30, 150mg solution reconstituted. However, using prescription discount cards available at most pharmacies can substantially lower this cost. The generic form Colistimethate Sodium (Cba) is considerably less expensive than its brand-name counterpart, Coly-Mycin M, making it an affordable option for uninsured patients seeking cost savings.

How does insurance affect the price I pay for Colistimethate Sodium (Cba)?

Insurance coverage for Colistimethate Sodium (Cba) depends entirely on your specific plan—not all plans cover this medication. To determine your exact copay and whether your plan includes Colistimethate Sodium (Cba), contact your insurance provider directly. If your insurance does not cover it, or if you have Medicare or Medicaid, you can use pharmacy discount cards to find competitive prices at local pharmacies. Comparing your insurance copay with discount card prices at different locations may reveal which option offers the lowest out-of-pocket expense.

What is the brand-name version of Colistimethate Sodium (Cba)?

Coly-Mycin M is the brand-name form of Colistimethate Sodium (Cba). While both contain identical active ingredients, the generic Colistimethate Sodium (Cba) is typically far more affordable than the brand-name product, making it a cost-effective choice for most patients.

Colistimethate prices at US pharmacies

(Colistimethate Sodium (Cba)) — solution reconstituted, 150mg, qty 30

PharmacyRetail priceWith discount card
CVS Pharmacy Lowest $210.75 $207.75
Walgreens $483.10 $480.10
Publix $508.42 $505.42
Kroger Pharmacy $759.68 $756.68
Harris Teeter Pharmacy $759.68 $756.68
Walmart Neighborhood Market $813.16 $810.16
Walmart Pharmacy $813.16 $810.16

Coly-Mycin M (Colistimethate Sodium (Cba)) — solution reconstituted, 150mg, qty 6

PharmacyRetail priceWith discount card
CVS Pharmacy Lowest $210.75 $207.75
Walgreens $483.10 $480.10
Publix $508.42 $505.42
Kroger Pharmacy $759.68 $756.68
Harris Teeter Pharmacy $759.68 $756.68
Walmart Neighborhood Market $813.16 $810.16
Walmart Pharmacy $813.16 $810.16

Colistimethate prices at Canadian pharmacies

StrengthPharmacyPer pill (USD)Pack total
Default GoldStarMeds.com $78.94 $78.94
Default 1800RxOnline.com $87.71 $87.71
StrengthPharmacyPer pill (USD)Pack total
Default GoldStarMeds.com $76.91 $76.91
Default 1800RxOnline.com $85.46 $85.46
StrengthPharmacyPer pill (USD)Pack total
Default GoldStarMeds.com $76.91 $76.91
Default 1800RxOnline.com $85.46 $85.46

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Colistimethate used for?

Colistimethate Sodium (Cba) is an antibiotic belonging to the polymyxins drug class, manufactured by Avet Pharmaceuticals. The typical retail price is $1,306.36 per 30, 150mg solution reconstituted. Colistimethate Sodium (Cba) is a generic medication; Coly-Mycin M is its brand-name equivalent. Discount cards and pharmacy price-comparison tools can help reduce out-of-pocket costs significantly.

Available forms

solution reconstituted

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

CONTRAINDICATIONS The use of Colistimethate for Injection, USP is contraindicated for patients with a history of sensitivity to the drug or any of its components.

Warnings

WARNINGS Maximum daily dose calculated from colistin base activity should not exceed 5 mg/kg/day with normal renal function. Transient neurological disturbances may occur. These include circumoral paresthesia or numbness, tingling or formication of the extremities, generalized pruritus, vertigo, dizziness, and slurring of speech. For these reasons, patients should be warned not to drive vehicles or use hazardous machinery while on therapy. Reduction of dosage may alleviate symptoms. Therapy need not be discontinued, but such patients should be observed with particular care. Nephrotoxicity can occur and is probably a dosedependent effect of colistimethate sodium.

Known drug interactions

Drug Interactions Certain other antibiotics (aminoglycosides and polymyxin) have also been reported to interfere with the nerve transmission at the neuromuscular junction. Based on this reported activity, they should not be given concomitantly with Colistimethate for Injection, USP except with the greatest caution. Curariform muscle relaxants (e.g., tubocurarine) and other drugs, including ether, succinylcholine, gallamine, decamethonium and sodium citrate, potentiate the neuromuscular blocking effect and should be used with extreme caution in patients being treated with Colistimethate for Injection, USP.

Pregnancy & breastfeeding

Pregnancy Teratogenic Effects Pregnancy Category C Colistimethate sodium given intramuscularly during organogenesis to rabbits at 4.15 and 9.3 mg/kg resulted in talipes varus in 2.6% and 2.9% of fetuses, respectively. These doses are 0.25 and 0.55 times the maximum daily human dose based on mg/m 2 . In addition, increased resorption occurred at 9.3 mg/kg. Colistimethate sodium was not teratogenic in rats at 4.15 or 9.3 mg/kg.

Colistimethate, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$4.1M
Medicare Part D spend, 2024
4.6K
Medicare Part D claims, 2024
7
FDA-listed manufacturers (Orange Book)
$5.2
Federal (VA) contract price per pack (1)

Frequently asked questions

How much does Colistimethate cost without insurance?
Retail (no-insurance) prices we found for Colistimethate range up to about $813.16 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $207.75. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Colistimethate?
Yes — our pricing data includes at least one generic listing for Colistimethate. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Colistimethate in?
Colistimethate belongs to the polymyxins class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.