Mupirocin — Compare Prices at US & Canada Pharmacies

Mupirocin is a prescription topical antibiotic designed to treat localized bacterial skin infections, particularly impetigo caused by Staphylococcus aureus and Streptococcus pyogenes. It can also be used to prevent or treat Staph infections in the nasal passages. The medication halts bacterial growth and multiplication at the site of application. Mupirocin is formulated as a 2% cream and 2% ointment for topical use. Your healthcare provider will determine the appropriate formulation and treatment regimen based on the type and severity of your infection. Apply the medication only to affected skin or nasal areas as directed; do not ingest it. After applying mupirocin to the nose, gently press the sides of your nose together for about one minute to distribute the ointment evenly inside the nasal cavity. If the medication contacts your mouth or eyes, rinse immediately with water. Always wash your hands before and after application. Most skin infections should show improvement within three to five days; contact your doctor if symptoms persist beyond this timeframe.

Localized side effects—such as mild burning, itching, stinging, or general skin irritation at the application site—are common and typically resolve on their own. If these symptoms persist or intensify, discontinue use and speak with your healthcare provider. Rarely, mupirocin use has been associated with serious intestinal infections caused by Clostridium difficile, particularly when absorbed systemically. Warning signs include persistent diarrhea, abdominal cramping, and bloody or mucus-containing stools; seek immediate medical care if any of these develop. Severe allergic reactions, though uncommon, can occur and may present as severe rash, facial or throat swelling, or respiratory difficulty—contact emergency services if you experience these symptoms. Secondary infections from fungi or other organisms may develop due to disruption of normal skin flora. This is not an exhaustive list of possible side effects. Speak with your healthcare provider or pharmacist about the complete risk-benefit profile of mupirocin and any concerns regarding potential drug interactions.

Mupirocin is a topical antibiotic effective against bacterial skin infections caused by susceptible bacterial strains. Primary uses include treatment of impetigo and prevention or treatment of nasal Staph infections. The medication is not effective against viral, fungal, or parasitic infections.