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Penicillinase-Resistant Penicillins WHO AWaRe: Access Prescription only

Oxacillin — Compare Prices at US & Canada Pharmacies

Compare real Oxacillin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Penicillinase-Resistant Penicillins
Common forms
Injectable (reconstituted)
Generic available
Yes
Legal status
Prescription only

What is the typical out-of-pocket cost for Oxacillin Sodium In Dextrose without insurance?

The standard retail price for Oxacillin Sodium In Dextrose without insurance coverage is approximately $14.01 per 2gm/50ml IV solution. However, the actual cost can vary considerably depending on the pharmacy. Many patients find that comparing prices across different pharmacies or using available discount programs can reduce their out-of-pocket expense. Since this is a generic medication, it is typically more affordable than any branded equivalent would be.

What is the cost of Oxacillin Sodium In Dextrose when covered by insurance?

Insurance coverage and out-of-pocket costs for Oxacillin Sodium In Dextrose depend entirely on your specific plan's formulary and your individual copay or coinsurance terms. To learn your exact coverage and cost-sharing amount, contact your insurance provider directly with your prescription details. If your plan does not cover this medication or if your copay is high, you may want to check pharmacy discount programs or compare pricing at multiple pharmacies to find more affordable options. This applies whether you have standard commercial insurance, Medicare, or Medicaid.

Oxacillin prices at US pharmacies

Oxacillin Sodium In Dextrose — solution (quantity in ml), 2gm/50ml, qty 24

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $16.47 $13.47
Harris Teeter Pharmacy $16.47 $13.47
Walmart Neighborhood Market $17.82 $14.82
Walmart Pharmacy $17.82 $14.82
Walgreens $18.78 $15.78
Publix $20.10 $17.10
CVS Pharmacy $36.18 $33.18

(Oxacillin Sodium) — solution reconstituted, 2gm, qty 12

PharmacyRetail priceWith discount card
Walgreens Lowest $48.22 $45.22
CVS Pharmacy $113.09 $110.09
Publix $180.76 $177.76
Kroger Pharmacy $258.38 $255.38
Harris Teeter Pharmacy $258.38 $255.38
Walmart Neighborhood Market $278.44 $275.44
Walmart Pharmacy $278.44 $275.44

Oxacillin prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Oxacillin in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Oxacillin used for?

Oxacillin Sodium In Dextrose is a penicillinase-resistant penicillin antibiotic available as a generic prescription medication, manufactured by Baxter Healthcare Corp. The average retail price for a 2gm/50ml intravenous solution is $14.01, though uninsured patients may find significantly lower prices by comparing rates across different pharmacies.

Available forms

solution (quantity in ml), solution reconstituted

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

CONTRAINDICATIONS A history of a hypersensitivity (anaphylactic) reaction to any penicillin is a contraindication.

Warnings

WARNINGS Serious and occasionally fatal hypersensitivity (anaphylactic shock with collapse) reactions have occurred in patients receiving penicillin. The incidence of anaphylactic shock in all penicillin-treated patients is between 0.015 and 0.04 percent. Anaphylactic shock resulting in death has occurred in approximately 0.002 percent of the patients treated. When oxacillin therapy is indicated, it should be initiated only after a comprehensive patient drug and allergy history has been obtained. If an allergic reaction occurs, oxacillin should be discontinued and appropriate therapy instituted.

Known drug interactions

Drug Interactions Tetracycline, a bacteriostatic antibiotic, may antagonize the bactericidal effect of penicillin and concurrent use of these drugs should be avoided. Oxacillin blood levels may be increased and prolonged by concurrent administration of probenecid which blocks the renal tubular secretion of penicillins. Probenecid decreases the apparent volume of distribution and slows the rate of excretion by competitively inhibiting renal tubular secretion of penicillins. Oxacillin-probenecid therapy should be limited to those infections where very high serum levels of oxacillin are necessary.

Pregnancy & breastfeeding

Pregnancy Teratogenic Effects Reproduction studies performed in the mouse, rat, and rabbit have revealed no evidence of impaired fertility or harm to the fetus due to the penicillinase-resistant penicillins. Human experience with the penicillins during pregnancy has not shown any positive evidence of adverse effects on the fetus. There are, however, no adequate or well-controlled studies in pregnant women showing conclusively that harmful effects of these drugs on the fetus can be excluded.

Oxacillin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$2.2M
Medicare Part D spend, 2024
3.6K
Medicare Part D claims, 2024
17
FDA-listed manufacturers (Orange Book)
$45.77
Federal (VA) contract price per pack (10GM)

Frequently asked questions

How much does Oxacillin cost without insurance?
Retail (no-insurance) prices we found for Oxacillin range up to about $278.44 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $13.47. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Oxacillin?
Yes — our pricing data includes at least one generic listing for Oxacillin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Oxacillin in?
Oxacillin belongs to the penicillinase-resistant penicillins class of antibiotics. WHO classifies it as an 'Access' antibiotic under its AWaRe stewardship framework.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.