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Oxazolidinones WHO AWaRe: Reserve

Sivextro — Compare Prices at US & Canada Pharmacies

Compare real Sivextro prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Oxazolidinones
Common forms
Tablet
Generic available
Brand only

What is the typical out-of-pocket cost for Sivextro without insurance coverage?

Without insurance, Sivextro typically costs around $3,990.02 at most pharmacies. However, patients may reduce this cost by exploring available discount programs or comparing prices across different pharmacies. Many prescription discount cards and manufacturer savings programs can help lower the final price at the point of sale.

How much might patients pay for Sivextro if they have insurance?

Sivextro costs with insurance depend on your specific plan's formulary status, copay tier, and deductible. The medication carries an average retail price of $3,990.02 per 7-pack of 200mg tablets. Your out-of-pocket cost may differ from the uninsured price, and it's worth comparing your insurance copay against available discount options. Ask your pharmacist to help you identify the most affordable option for your particular situation.

Do Medicare plans cover Sivextro, and what are typical patient costs?

Coverage for Sivextro varies among Medicare plans, and beneficiaries may encounter substantial copayments where coverage exists. Those enrolled in a Medicare plan that does cover Sivextro should verify their specific out-of-pocket responsibility before filling a prescription. Prescription discount cards may offer an alternative pricing option worth exploring with your pharmacist.

Is a generic version of Sivextro available?

Sivextro is available only as a brand-name medication. No generic formulation has been approved or is currently available in the United States market.

Sivextro prices at US pharmacies

Sivextro — tablet, 200mg, qty 7

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $3366.24 $3363.24
Harris Teeter Pharmacy $3366.24 $3363.24
CVS Pharmacy $3507.36 $3504.36
Food Lion $3527.95
Walgreens $3533.63 $3530.63
Publix $3555.59 $3552.59
Walmart Neighborhood Market $3615.22 $3612.22
Walmart Pharmacy $3615.22 $3612.22

Sivextro prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Sivextro in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Sivextro used for?

Sivextro is an FDA-approved antibiotic prescribed to treat specific bacterial skin infections, particularly those caused by Staphylococcus aureus. As a brand-name medication, Sivextro has no generic equivalent currently available in the United States. The typical retail cost is approximately $3,990.02, though prices may vary depending on your pharmacy and available discount programs.

Available forms

tablet

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

4 CONTRAINDICATIONS None None ( 4 )

Known drug interactions

7 DRUG INTERACTIONS Orally administered SIVEXTRO inhibits Breast Cancer Resistance Protein (BCRP) in the intestine, which can increase the plasma concentrations of orally administered BCRP substrates, and the potential for adverse reactions. If possible, an interruption in the treatment of the co-administered BCRP substrate medicinal product should be considered during treatment with SIVEXTRO, especially for BCRP substrates with a narrow therapeutic index (e.g., methotrexate or topotecan). If coadministration cannot be avoided, monitor for adverse reactions related to the concomitantly administered BCRP substrates, including rosuvastatin.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary Based on animal reproduction studies, SIVEXTRO may cause fetal harm when administered to pregnant women. The available data on the use of SIVEXTRO in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes. Advise pregnant women of the potential risks to a fetus. Fetal developmental toxicities were observed in mice and rats treated with SIVEXTRO.

Sivextro, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$16.5M
Medicare Part D spend, 2024
1.5K
Medicare Part D claims, 2024
$1920.2
Federal (VA) contract price per pack (6)

Frequently asked questions

How much does Sivextro cost without insurance?
Retail (no-insurance) prices we found for Sivextro range up to about $3615.22 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $3363.24. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Sivextro?
We did not find a generic listing for Sivextro in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Sivextro in?
Sivextro belongs to the oxazolidinones class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Learn more about Sivextro

In-depth answers to common Sivextro questions, fact-checked against the sources cited in each.

What is Sivextro and how does it work?

Sivextro is an antibiotic used to treat acute bacterial skin infections, especially those caused by Staphylococcus aureus (staph) bacteria. The medication is ineffective against viral infections such as the common cold or influenza. Staph bacteria naturally inhabit human skin and nasal passages without typically causing harm, but can trigger serious infections if they penetrate deeper tissues, enter the bloodstream, or spread to joints, bones, heart, or lungs. Sivextro is not approved for use in children under age 12. The medication comes in two forms: oral tablets and an injectable powder. Patients must take Sivextro exactly as prescribed and complete the entire treatment course to achieve full recovery from the infection. Healthcare professionals emphasize that improper antibiotic use—including incomplete courses or misuse—accelerates the development of drug-resistant bacteria, which diminishes the medication's future effectiveness.

What side effects should patients be aware of when taking Sivextro?

Common side effects include headache, nausea, vomiting, diarrhea, and dizziness. Patients receiving injections may experience pain or bruising at the injection site. Seek emergency medical care if you develop signs of an allergic reaction such as hives, facial swelling, throat or tongue swelling, or breathing difficulty. Contact your doctor or go to the nearest emergency department if you experience watery or bloody diarrhea, severe abdominal pain, or symptoms suggesting low blood cell counts—including fever, chills, unusual fatigue, excessive bruising, or abnormal bleeding. This is not an exhaustive list of potential side effects. Discuss all known risks and benefits of Sivextro with your healthcare provider to determine whether it is appropriate for your specific health situation.


Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.