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Amebicides

Solosec — Compare Prices at US & Canada Pharmacies

Compare real Solosec prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Amebicides
Generic available
Brand only

What is the out-of-pocket cost of Solosec at retail prices?

The average out-of-pocket retail price for Solosec is $408.52 for a single 1-packet box. Actual costs may differ depending on your pharmacy location and current pricing. Using prescription discount cards or manufacturer coupons available through various sources may help lower your out-of-pocket expense at participating pharmacy locations.

What will I pay for Solosec if my insurance covers it?

Solosec coverage through insurance depends on your specific plan, the quantity prescribed, and your individual coverage details. Your plan may cover a portion of the medication cost, leaving you responsible for a copay or coinsurance amount. Comparing retail prices and discount programs with your insurance copay is often worthwhile, as sometimes the discount option proves more economical. Contact your insurance provider or speak with your pharmacist to determine your exact out-of-pocket cost under your plan.

Does Medicare include Solosec in its coverage, and at what cost?

Medicare coverage for Solosec depends on which specific plan you have enrolled in. Review your plan's drug formulary or speak with your pharmacist to confirm whether your Medicare Part D or Medicare Advantage plan includes Solosec coverage. In certain situations, using prescription discount programs available through retailers may offer greater savings than your Medicare copay. Reach out to your plan administrator or local pharmacy for details on your actual cost.

Is a generic version of Solosec available?

Secnidazole is the generic name for Solosec's active ingredient. Currently, no generic formulation of Solosec has been approved or made available in the U.S. market.

Solosec prices at US pharmacies

Solosec — box, 1 packet, qty 1

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $293.10 $290.10
Harris Teeter Pharmacy $293.10 $290.10
Walgreens $308.99 $305.99
Food Lion $308.48
Publix $312.01 $309.01
Walmart Neighborhood Market $314.82 $311.82
Walmart Pharmacy $314.82 $311.82
Costco $316.08 $313.08

Solosec prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Solosec in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Solosec used for?

Solosec is a prescription medication prescribed to treat bacterial vaginosis, a prevalent vaginal infection affecting women, and trichomoniasis, a parasitic sexually transmitted infection. The active ingredient, secnidazole, functions by eliminating bacteria and parasites while suppressing their reproduction. The typical retail price for Solosec is $408.52 per 1-packet box. Prescription discount programs and coupons available through various retailers may help reduce this cost at participating pharmacies.

Available forms

box

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

4. CONTRAINDICATIONS SOLOSEC is contraindicated: In patients who have shown hypersensitivity to secnidazole, or other nitroimidazole derivatives. In patients with Cockayne syndrome: Severe irreversible hepatotoxicity/acute liver failure with fatal outcomes have been reported after initiation of metronidazole, another nitroimidazole drug, structurally related to secnidazole, in patients with Cockayne syndrome [see Adverse Reactions (6.2) ] .

Known drug interactions

7 DRUG INTERACTIONS 7.1 Oral Contraceptives There was no clinically significant drug interaction between secnidazole and the combination oral contraceptive, ethinyl estradiol plus norethindrone [see Clinical Pharmacology (12.3) ] . SOLOSEC can be co-administered with combination oral contraceptives (e.g., ethinyl estradiol plus norethindrone). 7.2 Alcohol Alcoholic beverages and preparations containing ethanol or propylene glycol should be avoided during SOLOSEC therapy and for 2 days after treatment is stopped.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary Limited available data with SOLOSEC use in pregnant women are insufficient to inform a drug associated risk of adverse developmental outcomes . In animal reproduction studies, there were no adverse developmental outcomes when secnidazole was administered orally to pregnant rats and rabbits during organogenesis at doses up to 4 times the clinical dose (see Data ).

Solosec, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$0.1M
Medicare Part D spend, 2024
190
Medicare Part D claims, 2024
$172.08
Federal (VA) contract price per pack (1)

Frequently asked questions

How much does Solosec cost without insurance?
Retail (no-insurance) prices we found for Solosec range up to about $316.08 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $290.10. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Solosec?
We did not find a generic listing for Solosec in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Solosec in?
Solosec belongs to the amebicides class of antibiotics.

Learn more about Solosec

In-depth answers to common Solosec questions, fact-checked against the sources cited in each.

What is Solosec and how does it work?

Solosec is an oral prescription medication approved to treat bacterial vaginosis and trichomoniasis in patients aged 12 and older. Its distinguishing feature is that it delivers a complete treatment course in a single dose. The medication works by interfering with bacterial and parasitic cell function and preventing their growth and reproduction. Classified as a nitroimidazole antimicrobial agent, secnidazole disrupts the ability of these microorganisms to proliferate.

What dosage strengths does Solosec come in?

Solosec is formulated as a single 2-gram dose supplied as oral granules. The granules should be sprinkled onto soft foods such as applesauce, yogurt, or pudding and consumed entirely within 30 minutes without chewing the individual granules. The medication is not designed to be mixed into liquids. This single-dose regimen represents one of Solosec's key advantages in terms of convenience and ease of use.

What adverse reactions can occur with Solosec?

Solosec may produce side effects, ranging from mild to serious. Frequently reported side effects include nausea, headache, vomiting, diarrhea, abdominal discomfort, vulvovaginal itching, and a metallic taste. Severe side effects are uncommon but can include anaphylactic reactions characterized by breathing difficulty, facial or throat swelling, or rash development. If you experience these serious symptoms after taking Solosec, seek emergency medical care immediately. The medication may also trigger secondary vaginal yeast infections. Discuss potential side effects, precautions, and possible drug interactions with your healthcare provider before beginning treatment.

How quickly does Solosec begin to relieve symptoms?

Solosec reaches peak blood concentration within approximately four hours and maintains therapeutic activity for roughly four days following a single dose. Symptom improvement typically becomes noticeable within several days of administration. Full resolution of bacterial vaginosis, however, may require three to four weeks according to clinical data.

How effective is Solosec in clinical studies?

Clinical trial data demonstrates that Solosec produces favorable outcomes for both bacterial vaginosis and trichomoniasis treatment. Approximately 50% of women with bacterial vaginosis experience a positive response to Solosec therapy, while approximately 90% of individuals treated for trichomoniasis achieve cure. Effectiveness varies among patients, so consult your physician if symptoms persist or worsen following treatment.

How does Solosec compare to metronidazole?

Solosec and metronidazole are distinct medications with different active ingredients and treatment protocols. Although both demonstrate comparable effectiveness for bacterial vaginosis, Solosec contains secnidazole while metronidazole is a separate generic antibiotic compound. They differ in their dosing schedules and side effect profiles. Your healthcare provider can recommend which option best suits your clinical situation and medical history.


Sources

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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.