Vabomere — Compare Prices at US & Canada Pharmacies
Compare real Vabomere prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.
What is the cash price of Vabomere for patients without insurance?
The standard retail price of Vabomere without health insurance coverage is approximately $1,305.75 per 3, 2 (1-1)gm solution reconstituteds. Patients may be able to lower this cost by using pharmacy discount programs or checking for manufacturer patient assistance programs, which can reduce the price to around $687.85 per 3, 2 (1-1)gm solution reconstituteds. Comparing prices across different pharmacies and discount options is recommended to find the lowest available cost.
What does Vabomere cost if I have insurance coverage?
Insurance coverage for Vabomere depends on your specific plan's formulary and coverage decisions. Your out-of-pocket cost will be determined by your copay, coinsurance, or deductible as defined in your policy. To find your exact cost under your insurance plan, contact your insurance company directly or check your plan's formulary. If your insurance does not cover Vabomere, if your copay is high, or if you have Medicare or Medicaid, you may want to explore pharmacy discount programs or manufacturer assistance options to compare total costs.
Is a generic version of Vabomere available?
Vabomere is a brand-name medication manufactured by Melinta Therapeutics. Currently, no generic equivalent has been approved or is available in the United States.
Vabomere prices at US pharmacies
Vabomere — solution reconstituted, 2 (1-1)gm, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Kroger Pharmacy Lowest | $690.85 | $687.85 |
| Harris Teeter Pharmacy | $690.85 | $687.85 |
| Walgreens | $726.26 | $723.26 |
| Publix | $731.72 | $728.72 |
| CVS Pharmacy | $734.90 | $731.90 |
| Walmart Neighborhood Market | $741.85 | $738.85 |
| Walmart Pharmacy | $741.85 | $738.85 |
| Costco | $745.55 | $742.55 |
Vabomere prices at Canadian pharmacies
No Canadian pharmacy pricing was found for Vabomere in our latest data pull.
Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.
What is Vabomere used for?
Vabomere combines meropenem with vaborbactam, a beta-lactamase inhibitor developed specifically to counter KPC (Klebsiella pneumoniae carbapenemase) — the single most common resistance mechanism behind carbapenem-resistant Enterobacterales infections in the US. That targeted design is what sets Vabomere apart from other carbapenem combinations like Recarbrio: vaborbactam is especially effective at restoring meropenem's activity specifically against KPC-producing organisms, making Vabomere a go-to option when a resistant infection is confirmed or strongly suspected to involve this particular resistance enzyme. It's FDA-approved specifically for complicated urinary tract infections, including pyelonephritis, in adults — a narrower approved indication than some other reserve carbapenems, reflecting the specific trials that supported its approval.
Because it's built on meropenem, Vabomere carries that drug's core carbapenem risks: seizure potential (lower than imipenem-cilastatin but not zero, especially with renal impairment), and a documented interaction with valproic acid or divalproex sodium, where carbapenems can significantly lower valproate blood levels and risk breakthrough seizures in patients relying on it for seizure control — a combination generally avoided, with an alternative antibacterial class considered instead when possible.
As a targeted, resistance-specific reserve antibiotic, Vabomere sits in WHO's Reserve AWaRe category. It's meant to be used when confirmed or strongly suspected carbapenem-resistant infection justifies it, both to preserve its effectiveness against an already-difficult-to-treat resistance mechanism and because it isn't appropriate for infections that would respond to standard therapy.
How Vabomere works
Blocks bacterial cell wall synthesis
Meropenem binds to penicillin-binding proteins and stops bacteria from building their cell wall, the core carbapenem mechanism.
Vaborbactam overcomes KPC resistance
Vaborbactam specifically inhibits KPC enzymes, the most common resistance mechanism behind carbapenem-resistant Enterobacterales in the US, restoring meropenem's effectiveness against these strains.
The bacterial cell dies
Without an intact cell wall, the bacterium ruptures and dies — even strains that would otherwise defeat meropenem alone through KPC production.
Typical dosage forms & strengths
| Use | Typical adult dose | Form |
|---|---|---|
| Complicated UTI, including pyelonephritis (adults) | 4 g (meropenem 2 g/vaborbactam 2 g) IV every 8 hours, adjusted for kidney function | IV infusion (reconstituted) |
General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.
Related & alternative drugs
Commonly used for
Warnings & interactions
This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.
Common, usually mild
- Headache
- Diarrhea
- Injection site reactions
Serious — seek care promptly
- Seizures, especially with kidney impairment
- Signs of a severe allergic reaction
- Severe or persistent diarrhea (possible C. difficile infection)
Contraindications
4 CONTRAINDICATIONS VABOMERE is contraindicated in patients with known hypersensitivity to any components of VABOMERE (meropenem and vaborbactam), or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactam antibacterial drugs [see Warnings and Precautions ( 5.1 )] . Known hypersensitivity to the components of VABOMERE (meropenem and vaborbactam) or anaphylactic reactions to beta‑lactams. ( 4 )
Notable drug interactions
| Drug / substance | What can happen |
|---|---|
| Valproic acid / divalproex sodium | Can significantly lower valproate levels and risk breakthrough seizures; combination generally avoided |
Frequently asked questions
How much does Vabomere cost without insurance?
Is there a generic version of Vabomere?
What drug class is Vabomere in?
Page info
Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.
Christopher J. Graber, M.D., MPH, FIDSA, Infectious Disease