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Cephalosporins - 4th Generation WHO AWaRe: Watch Prescription only

Cefepime Dextrose — Compare Prices at US & Canada Pharmacies

Compare real Cefepime Dextrose prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Cephalosporins - 4th Generation
Common forms
Premixed IV solution
Key risk
Neurotoxicity with renal impairment
Generic available
Yes
Legal status
Prescription only

What is the typical out-of-pocket cost for Cefepime-Dextrose without insurance?

The average retail price for Cefepime-Dextrose without health insurance coverage is approximately $18.11 per 2–5 gm vial (50 mL solution reconstituted). Uninsured patients may also explore pharmacy discount programs or price-comparison tools to locate lower rates at different locations. Because Cefepime-Dextrose is a generic medication rather than a brand-name formulation, it generally offers more affordable pricing than branded alternatives.

How does insurance coverage affect the price of Cefepime-Dextrose?

Insurance coverage for Cefepime-Dextrose varies significantly depending on your specific drug plan and formulary. To determine your actual copay or coinsurance, contact your insurance provider directly and ask whether Cefepime-Dextrose appears on their covered medications list. If your plan does not include this medication, you may have the option to use pharmacy discount programs or compare prices across different pharmacies to find the most affordable rate. Those with Medicare or Medicaid should verify coverage details with their plan administrator, as coverage policies differ by plan type and individual eligibility.

Cefepime Dextrose prices at US pharmacies

Cefepime-Dextrose — solution reconstituted, 2-5gm-%(50ml), qty 1

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $34.19 $31.19
Harris Teeter Pharmacy $34.19 $31.19
Walmart Neighborhood Market $36.85 $33.85
Walmart Pharmacy $36.85 $33.85
Walgreens $37.38 $34.38
Publix $38.81 $35.81
CVS Pharmacy $54.55 $51.55

Cefepime Dextrose prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Cefepime Dextrose in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Cefepime Dextrose used for?

Cefepime-dextrose is the same fourth-generation cephalosporin as standard cefepime, supplied premixed in a ready-to-infuse dextrose IV solution instead of a powder that needs reconstitution. That's purely a formulation convenience — the medication, its FDA-approved uses (pneumonia, urinary tract infections, skin infections, complicated intra-abdominal infections with metronidazole, and febrile neutropenia), and its precautions are the same as plain cefepime.

The same neurotoxicity concern applies here as with standard cefepime: confusion, altered mental status, and seizures have been reported, especially when the dose isn't reduced appropriately for a patient's kidney function — kidney function is checked before and monitored during therapy for exactly this reason.

As a premixed dextrose solution, this formulation may not be appropriate for patients with a known corn allergy, since dextrose is typically corn-derived; it's otherwise handled the same way as cefepime supplied as a powder for reconstitution.

How Cefepime Dextrose works

  1. Attacks the bacterial cell wall

    Like other cephalosporins, cefepime blocks the enzymes bacteria need to build and maintain their cell wall.

  2. Reaches bacteria other cephalosporins miss

    Its structure lets it penetrate the outer membrane of many gram-negative bacteria, including Pseudomonas, that earlier-generation cephalosporins can't reliably reach.

  3. The bacterial cell dies

    Without an intact wall, the bacterium ruptures and dies.

Typical dosage forms & strengths

UseTypical adult doseForm
Pneumonia, UTI, skin infections, febrile neutropenia (adults, normal kidney function)0.5–2 g IV every 8–12 hours, depending on infection and severityPremixed IV infusion

General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Injection-site irritation
  • Nausea, diarrhea

Serious — seek care promptly

  • Confusion, altered mental status, or seizures (neurotoxicity — risk increases with impaired kidney function)
  • Signs of an allergic reaction: hives, facial/throat swelling, trouble breathing
  • Severe or watery diarrhea (possible C. diff colitis)

Contraindications

4 CONTRAINDICATIONS Patients with known immediate hypersensitivity reactions to cefepime or other cephalosporins, penicillins or other beta-lactam antibacterial drugs. ( 4 ) 4.1 Hypersensitivity to Cefepime or the Cephalosporin Class of Antibacterials, Penicillins, or Other Beta-lactam Antibacterials Cefepime for Injection and Dextrose Injection is contraindicated in patients who have shown immediate hypersensitivity reactions to cefepime or the cephalosporin class of antibacterial drugs,…

Notable drug interactions

Drug / substanceWhat can happen
AminoglycosidesIncreased risk of kidney and hearing/balance toxicity when combined.
Potent diuretics (e.g., furosemide)Nephrotoxicity has been reported when combined with cephalosporins.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary There are no cases of cefepime exposure during pregnancy reported from postmarketing experience or from clinical trials. Available data from published observational studies and case reports over several decades with cephalosporin use in pregnant women have not established drug-associated risks of major birth defects, miscarriage or adverse maternal or fetal outcomes (see Data ). Cefepime crosses the placenta.

Cefepime Dextrose, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$1.6M
Medicare Part D spend, 2024
5.9K
Medicare Part D claims, 2024

Frequently asked questions

How much does Cefepime Dextrose cost without insurance?
Retail (no-insurance) prices we found for Cefepime Dextrose range up to about $54.55 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $31.19. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Cefepime Dextrose?
Yes — our pricing data includes at least one generic listing for Cefepime Dextrose. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Cefepime Dextrose in?
Cefepime Dextrose belongs to the cephalosporins - 4th generation class of antibiotics. WHO classifies it as an 'Watch' antibiotic under its AWaRe stewardship framework.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.