Clindamycin Phos Benzoyl Perox (Acanya, Neuac) — Compare Prices at US & Canada Pharmacies
Compare real Clindamycin Phos Benzoyl Perox prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.
What is the typical out-of-pocket cost for Clindamycin-Benzoyl Peroxide without insurance?
Patients paying cash without insurance typically face a full retail price of $148.13 per 45-gram tube (1.2-5% strength). However, prescription discount cards and coupon programs available at many pharmacies can reduce this cost significantly. Comparing prices across different pharmacy chains and using available discount coupons can help uninsured patients find better rates.
Will my health insurance cover Clindamycin-Benzoyl Peroxide?
Coverage varies by insurance plan. Some plans do cover this combination medication, though not all include it as a covered benefit. Many insurers that don't cover Clindamycin-Benzoyl Peroxide will cover clindamycin phosphate gel on its own (without benzoyl peroxide). Copay amounts depend on where your plan places the medication on its formulary tier. If your insurance declines coverage or the copay is high, prescription discount cards offer an alternative way to purchase this medication at a reduced price.
Is Clindamycin-Benzoyl Peroxide covered under Medicare?
Medicare Part D and Medicare Advantage plans typically cover Clindamycin-Benzoyl Peroxide, though coverage is not guaranteed for all beneficiaries. Most plans that do cover it assign it to a middle copay tier, which may result in a substantial out-of-pocket cost. If Medicare coverage is unavailable or the copay is unexpectedly high, patients can ask their pharmacist to compare the Medicare cost against prices available through prescription discount programs.
What brand-name products contain Clindamycin-Benzoyl Peroxide?
Brand-name versions of this combination medication include Onexton, Acanya, and Neuac.
Clindamycin Phos Benzoyl Perox prices at US pharmacies
Acanya (Clindamycin Phos-Benzoyl Perox) — pump btl, 50gm of 1.2-2.5%, qty 50
| Pharmacy | Retail price | With discount card |
|---|---|---|
| CVS Pharmacy Lowest | $47.08 | $44.08 |
| Walgreens | $68.60 | $65.60 |
| Kroger Pharmacy | $101.61 | $98.61 |
| Harris Teeter Pharmacy | $101.61 | $98.61 |
| Walmart Neighborhood Market | $108.62 | $105.62 |
| Walmart Pharmacy | $108.62 | $105.62 |
| Food Lion | $111.00 | — |
| Costco | $136.90 | — |
Onexton (Clindamycin Phos-Benzoyl Perox) — pump btl, 50gm of 1.2-3.75%, qty 50
| Pharmacy | Retail price | With discount card |
|---|---|---|
| CVS Pharmacy Lowest | $64.63 | $61.63 |
| Walgreens | $158.64 | $155.64 |
| Publix | $354.71 | $351.71 |
| Food Lion | $492.00 | — |
| Kroger Pharmacy | $557.14 | $554.14 |
| Harris Teeter Pharmacy | $557.14 | $554.14 |
| Walmart Neighborhood Market | $597.13 | $594.13 |
| Walmart Pharmacy | $597.13 | $594.13 |
(Clindamycin Phos-Benzoyl Perox) — tube, 45gm of 1.2-5%, qty 45
| Pharmacy | Retail price | With discount card |
|---|---|---|
| CVS Pharmacy Lowest | $34.38 | $31.38 |
| Kroger Pharmacy | $36.14 | $33.14 |
| Harris Teeter Pharmacy | $36.14 | $33.14 |
| Costco | $33.99 | — |
| Publix | $35.59 | — |
| Food Lion | $36.35 | — |
| Walgreens | $43.68 | $40.68 |
| Walmart Neighborhood Market | $58.85 | $55.85 |
Neuac (Clindamycin Phos-Benzoyl Perox) — tube of gel, 45gm of 1.2-5%, qty 45
| Pharmacy | Retail price | With discount card |
|---|---|---|
| CVS Pharmacy Lowest | $34.38 | $31.38 |
| Kroger Pharmacy | $36.14 | $33.14 |
| Harris Teeter Pharmacy | $36.14 | $33.14 |
| Costco | $33.99 | — |
| Publix | $35.59 | — |
| Food Lion | $36.35 | — |
| Walgreens | $43.68 | $40.68 |
| Walmart Neighborhood Market | $58.85 | $55.85 |
Clindamycin Phos Benzoyl Perox prices at Canadian pharmacies
No Canadian pharmacy pricing was found for Clindamycin Phos Benzoyl Perox in our latest data pull.
Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.
What is Clindamycin Phos Benzoyl Perox used for?
Clindamycin phosphate-benzoyl peroxide combines a topical antibiotic with benzoyl peroxide in a single acne product, sold under several brand names (Acanya, Neuac, Onexton) at different strength ratios. Pairing the two addresses acne from two directions at once: clindamycin reduces the population of Cutibacterium acnes bacteria and calms inflammation, while benzoyl peroxide works on the skin's surface to kill bacteria and help unclog pores — and, importantly, benzoyl peroxide also helps prevent those bacteria from developing resistance to clindamycin, something that can happen when a topical antibiotic is used alone for months.
This fixed combination saves a step compared with using clindamycin gel and benzoyl peroxide separately, though the trade-off is a single product with less flexibility to adjust each ingredient's strength independently. As with any clindamycin-containing product, enough of the antibiotic is absorbed through the skin that the FDA label carries a caution about C. diff-related colitis, even though this is rare with topical use — people with a history of ulcerative colitis, Crohn's disease, or prior antibiotic-associated colitis generally shouldn't use it.
Expect some dryness, peeling, or mild irritation when starting treatment, particularly with the higher-benzoyl-peroxide-strength versions like Onexton (3.75%) — using a gentle moisturizer and easing into daily use can help the skin adjust.
How Clindamycin Phos Benzoyl Perox works
Clindamycin reduces bacteria and inflammation
It suppresses growth of Cutibacterium acnes and calms the inflammatory response driving acne lesions.
Benzoyl peroxide clears the pore and limits resistance
It releases oxygen into the follicle to kill surface bacteria and helps prevent them from becoming resistant to the antibiotic component.
Fewer new breakouts form
Used consistently, the combination reduces both the bacterial and inflammatory drivers of acne more effectively than either ingredient alone.
Typical dosage forms & strengths
| Use | Typical adult dose | Form |
|---|---|---|
| Acne vulgaris | Apply a thin layer to affected areas once daily | Topical gel (strength varies by brand) |
General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.
Related & alternative drugs
Commonly used for
Clindamycin Phos Benzoyl Perox, by the numbers
Additional public data points beyond retail pricing — useful context, not a price quote.
Frequently asked questions
How much does Clindamycin Phos Benzoyl Perox cost without insurance?
Is there a generic version of Clindamycin Phos Benzoyl Perox?
Is Clindamycin Phos Benzoyl Perox currently in shortage?
What drug class is Clindamycin Phos Benzoyl Perox in?
Learn more about Clindamycin Phos Benzoyl Perox
In-depth answers to common Clindamycin Phos Benzoyl Perox questions, fact-checked against the sources cited in each.
Does Clindamycin-Benzoyl Peroxide qualify for Medicaid coverage?
Most state Medicaid programs do provide coverage for Clindamycin-Benzoyl Peroxide when used to treat acne, though this varies by state. Patients in states where Medicaid coverage is not available or limited can explore discount card options to reduce their medication costs.
What are the best ways to reduce the cost of Clindamycin-Benzoyl Peroxide?
Several strategies can help lower costs. Prescription discount cards are widely available and can offer substantial savings at participating pharmacies. Comparing prices between local pharmacies—prices vary—can reveal significant differences. Eligible individuals should consider enrolling in government assistance programs such as Medicaid, Medicare Extra Help, or patient assistance programs offered by manufacturers. Some 340B providers also offer subsidized medications to qualifying patients. When using any discount program, remember that prices change by location and pharmacy, so checking multiple sources is worthwhile before filling your prescription.
Are there lower-cost alternatives to Clindamycin-Benzoyl Peroxide?
Yes, several alternatives may cost less. Generic clindamycin phosphate cream or gel without benzoyl peroxide typically costs about two-thirds of the price for Clindamycin-Benzoyl Peroxide. Since benzoyl peroxide is available over-the-counter for just a few dollars, using these two products separately may save money while achieving similar results. Topical erythromycin is another more affordable option. Some formulations include added ingredients like zinc (anti-inflammatory) or tretinoin (accelerates skin cell turnover). Minocycline tablets are an oral antibiotic alternative, though they carry a higher risk of side effects compared to topical treatments. Other topical agents like azelaic acid work through different mechanisms—preventing bacterial growth rather than fighting infection—and are cheaper, though they may be less effective than combination products. Before switching medications, consult a healthcare provider to ensure any alternative is appropriate for your specific situation.
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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.
Aldon Li, M.D., FIDSA, Infectious Disease, Internal Medicine