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Cyclic Lipopeptides WHO AWaRe: Reserve

Daptomyc — Compare Prices at US & Canada Pharmacies

Compare real Daptomyc prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Cyclic Lipopeptides
Generic available
Yes

What is the typical out-of-pocket cost for daptomycin-sodium chloride without insurance?

Without health insurance coverage, the average retail price for daptomycin-sodium chloride 500 mg/50 ml is around $124.94 per vial, though this can fluctuate depending on your pharmacy and location. Many patients without insurance can access lower prices by using prescription discount cards or comparing prices across different pharmacies. Purchasing the generic version of daptomycin typically costs significantly less than the brand-name formulation.

How does insurance coverage affect daptomycin-sodium chloride costs?

Insurance coverage for daptomycin-sodium chloride varies widely based on your specific plan and formulary. To find out whether your plan covers this medication and what your copay or coinsurance would be, contact your insurance provider directly for accurate information. If your plan does not cover daptomycin-sodium chloride or carries a high out-of-pocket cost, you may find that using a prescription discount card or comparing prices at local and mail-order pharmacies provides a more affordable option than your insurance copay.

Daptomyc prices at US pharmacies

Daptomycin-Sodium Chloride — solution (quantity in ml), 500-0.9mg/50ml-%, qty 150

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $119.43 $116.43
Harris Teeter Pharmacy $119.43 $116.43
Walgreens $126.79 $123.79
Walmart Neighborhood Market $128.36 $125.36
Walmart Pharmacy $128.36 $125.36
Publix $128.74 $125.74
CVS Pharmacy $142.86 $139.86

Daptomyc prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Daptomyc in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Daptomyc used for?

Daptomycin-sodium chloride is a cyclic lipopeptide antibiotic manufactured by Baxter Healthcare Corp. and available as a generic medication. The typical cash price for a 500 mg/50 ml vial is approximately $124.94, though prices may vary by pharmacy and location. Discount programs and price-comparison tools can help reduce out-of-pocket costs for uninsured and underinsured patients.

Available forms

solution (quantity in ml)

Related & alternative drugs

Daptomycin

Frequently asked questions

How much does Daptomyc cost without insurance?
Retail (no-insurance) prices we found for Daptomyc range up to about $142.86 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $116.43. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Daptomyc?
Yes — our pricing data includes at least one generic listing for Daptomyc. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Daptomyc in?
Daptomyc belongs to the cyclic lipopeptides class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Sources

FDA Orange Book (generic equivalence) RxNorm (RxCUI 22299)

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.