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Monobactam Combinations WHO AWaRe: Reserve Prescription only

Emblaveo — Compare Prices at US & Canada Pharmacies

Compare real Emblaveo prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Monobactam Combinations
AWaRe category
Reserve
Common forms
IV infusion
Approved for
Limited/no alternative options (cIAI)
Generic available
Brand only
Legal status
Prescription only

What is the typical out-of-pocket cost for Emblaveo without health insurance?

The standard retail price for Emblaveo is $4,072.95 per 10 vials of 1.5-0.5 gm solution for reconstitution when purchased without insurance. However, uninsured patients may be able to lower this amount by using prescription discount programs or coupons, which are often available through pharmacy chains or online discount services. Prices can vary by pharmacy location and the specific discount program used.

What will Emblaveo cost if I have insurance coverage?

Insurance coverage for Emblaveo depends entirely on your specific plan. Some insurance policies may cover this medication while others do not. To find out whether your plan includes Emblaveo and what your out-of-pocket responsibility would be, contact your insurance company directly and ask about coverage, copayments, and coinsurance amounts. If your insurer does not cover Emblaveo or if your copay is high, you may want to compare prices using pharmacy discount programs or coupons available at major pharmacy chains. Patients with Medicare or Medicaid should also contact their respective programs to verify coverage details before filling a prescription.

Is a generic form of Emblaveo available?

Emblaveo is a brand-name medication manufactured by AbbVie. Currently, no generic equivalent has been approved by the FDA, so brand-name Emblaveo is the only formulation available in the United States.

Emblaveo prices at US pharmacies

Emblaveo — solution reconstituted, 1.5-0.5gm, qty 10

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $3362.96 $3359.96
Harris Teeter Pharmacy $3362.96 $3359.96
CVS Pharmacy $3503.47 $3500.47
Walgreens $3529.52 $3526.52
Publix $3551.37 $3548.37
Walmart Neighborhood Market $3610.69 $3607.69
Walmart Pharmacy $3610.69 $3607.69
Costco $3630.78 $3627.78

Emblaveo prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Emblaveo in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Emblaveo used for?

Emblaveo combines aztreonam (a monobactam antibiotic) with avibactam (a beta-lactamase inhibitor), and — used together with metronidazole — is FDA-approved for complicated intra-abdominal infections in adults who have limited or no other treatment options. It fills a specific gap in the antibiotic arsenal: aztreonam alone resists a class of resistance enzymes called metallo-beta-lactamases, but many resistant bacteria that produce those enzymes also produce a second type that would normally destroy aztreonam too — avibactam blocks that second type, restoring aztreonam's effectiveness against organisms that would otherwise defeat it on both fronts.

Because of this, Emblaveo is particularly relevant for certain hard-to-treat carbapenem-resistant Enterobacterales (CRE) infections that don't respond to more commonly used Reserve antibiotics. The FDA's approval was explicitly based on limited clinical data, reflecting how this drug reached patients through a pathway designed for serious infections with few alternatives, and the WHO AWaRe framework classifies it as a Reserve antibiotic for exactly this reason.

Emblaveo is given only by IV infusion, almost always in a hospital, and is meant to be used only when a resistant infection is confirmed or strongly suspected — not as a routine choice — both to protect patients and to help preserve its usefulness for the infections it was specifically developed to treat.

How Emblaveo works

  1. Aztreonam attacks the cell wall

    Like other beta-lactams, it blocks the enzymes gram-negative bacteria need to build their cell wall.

  2. Avibactam disables a key bacterial defense

    It inhibits a broad range of beta-lactamase enzymes, including some that would otherwise destroy aztreonam.

  3. Reaches infections other Reserve drugs can't

    Because aztreonam itself resists a different class of resistance enzymes (metallo-beta-lactamases), the combination covers resistant bacteria that defeat other antibiotics through either mechanism alone.

Available forms

solution reconstituted

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Infusion-site pain or irritation
  • Nausea, vomiting, diarrhea

Serious — seek care promptly

  • Signs of an allergic reaction: hives, swelling, difficulty breathing
  • Severe or watery diarrhea (possible C. diff colitis)

Contraindications

4 CONTRAINDICATIONS EMBLAVEO is contraindicated in patients with known hypersensitivity to the components of EMBLAVEO (aztreonam and avibactam) [see Warnings and Precautions ( 5.1 )] . Known hypersensitivity to the components of EMBLAVEO (aztreonam and avibactam). ( 4 )

Notable drug interactions

Drug / substanceWhat can happen
ProbenecidNot recommended — inhibits transporters that clear avibactam, potentially reducing its elimination.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary There are no data on the effects of EMBLAVEO use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal outcomes. Available data from case reports over several decades with aztreonam and over approximately a decade with avibactam have not identified a drug-associated risk of major birth defects, miscarriage or other maternal or fetal outcomes.

Frequently asked questions

How much does Emblaveo cost without insurance?
Retail (no-insurance) prices we found for Emblaveo range up to about $3630.78 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $3359.96. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Emblaveo?
We did not find a generic listing for Emblaveo in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Emblaveo in?
Emblaveo belongs to the monobactam combinations class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.