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Acne Antibiotics Prescription only

Amzeeq — Compare Prices at US & Canada Pharmacies

Compare real Amzeeq prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Acne Antibiotics (Tetracycline-class, topical)
Common forms
Topical foam
Age range
9 years and older
Generic available
Brand only
Legal status
Prescription only

What is the typical out-of-pocket cost of Amzeeq without insurance?

Without health insurance, Amzeeq typically costs around $721.15 per 30 gm can (4% strength). However, you may be able to lower this price by using manufacturer coupons, pharmacy discount programs, or by requesting the generic version, Minocycline HCl Micronized (Acne), which is often significantly cheaper than the brand-name version. Comparing prices across different pharmacies can also help you find more affordable options.

How much does Amzeeq cost if you have insurance?

Insurance coverage for Amzeeq varies depending on your specific plan. Your out-of-pocket cost will depend on your formulary coverage, deductible, copay, and coinsurance. Contact your insurance provider directly to find out whether Amzeeq is covered under your plan and what your actual cost will be. If your plan does not cover Amzeeq or the copay is high, you can ask your pharmacist to price the generic version, Minocycline HCl Micronized (Acne), or use pharmacy discount programs to compare prices across different locations.

What is the generic version of Amzeeq?

The generic equivalent of Amzeeq is Minocycline HCl Micronized (Acne). Both the brand-name and generic versions contain the same active ingredient and work the same way to treat acne. The generic version is typically significantly more affordable than Amzeeq, which costs approximately $721.15 per 30 gm can (4% strength). Ask your doctor or pharmacist whether switching to the generic option is appropriate for your treatment, as it can result in meaningful savings on your prescription.

Amzeeq prices at US pharmacies

Amzeeq — can, 30gm of 4%, qty 30

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $518.04 $515.04
Harris Teeter Pharmacy $518.04 $515.04
Walgreens $544.97 $541.97
Food Lion $543.07 —
Publix $549.37 $546.37
CVS Pharmacy $555.86 $552.86
Walmart Neighborhood Market $556.32 $553.32
Walmart Pharmacy $556.32 $553.32

Amzeeq prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Amzeeq in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Amzeeq used for?

Amzeeq is a topical foam containing minocycline, a tetracycline-class antibiotic, formulated specifically to treat inflammatory acne — the FDA has approved it for non-nodular moderate to severe acne vulgaris in patients 9 and older. It is not an oral antibiotic, and per its FDA label it hasn't been studied or approved for treating infections; its only approved use is acne.

The foam is designed to deliver minocycline directly into the skin's oil glands and hair follicles while limiting how much reaches the bloodstream — systemic absorption after once-daily use has been shown to be low. That distinguishes it from oral minocycline, which is absorbed throughout the body and carries more of the class's systemic risks, such as photosensitivity or tooth discoloration in children.

Even so, Amzeeq is still a tetracycline-class drug, so several of the class's standard precautions still apply: it isn't recommended during pregnancy, and it shouldn't be used in children under 9 because of the risk of permanent tooth discoloration. The foam is also flammable due to its alcohol content, so it should be kept away from open flame or heat while applying and drying.

How Amzeeq works

  1. Reaches the follicle

    The foam carries minocycline into the pores and oil glands where acne-causing bacteria and inflammation originate.

  2. Reduces bacteria and inflammation

    Minocycline suppresses growth of Cutibacterium acnes and has independent anti-inflammatory effects on the skin.

  3. Fewer new lesions form

    Over weeks of daily use, inflammatory bumps and pustules decrease as the follicle environment calms down.

Typical dosage forms & strengths

UseTypical adult doseForm
Moderate to severe inflammatory acne (ages 9+)Apply a thin layer to affected areas once dailyTopical foam (1.5% or 4%)

General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.

Related & alternative drugs

Commonly used for

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Application-site pain, dryness, or redness
  • Application-site itching or scaling
  • Headache

Serious — seek care promptly

  • Signs of an allergic reaction: rash, hives, swelling, trouble breathing
  • Severe sunburn-like reaction (photosensitivity) with sun exposure
  • Severe headache or vision changes (rare, more associated with oral tetracyclines)

Contraindications

4 CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any other ingredients within AMZEEQ. This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the ingredients within AMZEEQ. ( 4 )

Notable drug interactions

Drug / substanceWhat can happen
Oral penicillin antibioticsTetracyclines can theoretically blunt penicillin's bactericidal action if used systemically together — worth mentioning to your prescriber even though this is a topical product.
Blood thinners (e.g., warfarin)Tetracyclines can depress plasma prothrombin activity; anticoagulant doses may need monitoring.
Other topical acne treatments (retinoids, benzoyl peroxide)Combining drying acne treatments can increase skin irritation.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary Available data with AMZEEQ use in pregnant women are insufficient to evaluate for a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal outcomes. Systemic absorption of AMZEEQ in humans is low following once daily topical administration of AMZEEQ for 21 days [see Clinical Pharmacology ( 12.3 )] .

Frequently asked questions

How much does Amzeeq cost without insurance?
Retail (no-insurance) prices we found for Amzeeq range up to about $556.32 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $515.04. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Amzeeq?
We did not find a generic listing for Amzeeq in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Amzeeq in?
Amzeeq belongs to the acne antibiotics class of antibiotics.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.