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Aminoglycosides WHO AWaRe: Watch Prescription only

Tobramycin (Bethkis, Tobi) — Compare Prices at US & Canada Pharmacies

Compare real Tobramycin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Generic name Tobramycin
Also sold as
BethkisTobiTobrex
Drug class
Aminoglycosides
Common forms
Injectable (vial)
Generic available
Yes
Legal status
Prescription only

How does insurance coverage affect Tobramycin Sulfate pricing?

Insurance coverage for Tobramycin Sulfate varies by plan and carrier. Your out-of-pocket cost will depend on your specific policy's formulary, copay structure, and deductible status. To determine your exact coverage and cost-sharing responsibility, contact your insurance provider directly with your prescription details. If your plan does not cover Tobramycin Sulfate or carries a high copay, prescription discount cards available at many pharmacies may offer a lower price as an alternative.

Tobramycin prices at US pharmacies

Bethkis (Tobramycin) — plas cont, 4ml of 300mg/4ml, qty 224

PharmacyRetail priceWith discount card
Walgreens Lowest $2239.56 $2236.56
Publix $3433.49 $3430.49
Kroger Pharmacy $5237.05 $5234.05
Harris Teeter Pharmacy $5237.05 $5234.05

Tobi (Tobramycin) — plas cont, 5ml of 300mg/5ml, qty 280

PharmacyRetail priceWith discount card
Walgreens Lowest $324.80 $321.80
Kroger Pharmacy $952.16 $949.16
Harris Teeter Pharmacy $952.16 $949.16
Publix $3547.89 $3544.89

Tobramycin — solution (quantity in ml), 0.3%, qty 5

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $5.99 $2.99
Harris Teeter Pharmacy $5.99 $2.99
Walmart Neighborhood Market $7.07 $4.07
Walmart Pharmacy $7.07 $4.07
Costco $12.99
Food Lion $13.00
Publix $17.53 $14.53
CVS Pharmacy $26.58 $23.58

Tobrex (Tobramycin) — tube, 3.5gm of 0.3%, qty 3.5

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $5.99 $2.99
Harris Teeter Pharmacy $5.99 $2.99
Walmart Neighborhood Market $7.07 $4.07
Walmart Pharmacy $7.07 $4.07
Costco $12.99
Food Lion $13.00
Publix $17.53 $14.53
CVS Pharmacy $26.58 $23.58

Tobramycin Sulfate — vial, 2ml of 80mg/2ml, qty 2

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $7.69 $4.69
Harris Teeter Pharmacy $7.69 $4.69
Walmart Neighborhood Market $10.25 $7.25
Walmart Pharmacy $10.25 $7.25
Food Lion $9.95
CVS Pharmacy $13.99 $10.99
Costco $12.19
Publix $16.25 $13.25

Tobramycin prices at Canadian pharmacies

StrengthPharmacyPer pill (USD)Pack total
0.3 %/0.1 % medsengage.com $3.38 $50.72
0.3 %/0.1 % medsengage.com $3.57 $35.69
StrengthPharmacyPer pill (USD)Pack total
0.3 %/0.1 % medsengage.com $3.38 $50.72
0.3 %/0.1 % medsengage.com $3.57 $35.69
StrengthPharmacyPer pill (USD)Pack total
0.30 % InhalersOnline.com $4.99 $99.72
0.30 % SPFPharmacy.com $5.43 $81.48
0.30 % InhalersOnline.com $5.80 $86.94
0.30 % SPFPharmacy.com $9.02 $45.10
StrengthPharmacyPer pill (USD)Pack total
0.30 % SPFPharmacy.com $7.35 $102.92
0.30 % InhalersOnline.com $11.85 $124.44
0.30 % SPFPharmacy.com $12.61 $44.13
0.30 % InhalersOnline.com $15.97 $55.90

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Tobramycin used for?

Tobramycin Sulfate is an aminoglycoside antibiotic manufactured by Fresenius Kabi Usa and available as a generic medication. The typical retail price is $12.73 per 2ml vial (80mg/2ml), though patients may find lower prices by comparing rates across different pharmacies. Using prescription discount cards or coupons can reduce out-of-pocket costs significantly.

Available forms

plas cont, solution (quantity in ml), tube, vial

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Boxed warning

WARNINGS Patients treated with Tobramycin Injection and other aminoglycosides should be under close clinical observation, because these drugs have an inherent potential for causing ototoxicity and nephrotoxicity. Neurotoxicity, manifested as both auditory and vestibular ototoxicity, can occur. The auditory changes are irreversible, are usually bilateral, and may be partial or total. Eighth-nerve impairment and nephrotoxicity may develop, primarily in patients having pre-existing renal damage and in those with normal renal function to whom aminoglycosides are administered for longer periods or in higher doses than those recommended.

Contraindications

CONTRAINDICATIONS A hypersensitivity to any aminoglycoside is a contraindication to the use of tobramycin. A history of hypersensitivity or serious toxic reactions to aminoglycosides may also contraindicate the use of any other aminoglycoside because of the known cross-sensitivity of patients to drugs in this class.

Warnings

WARNINGS See WARNINGS box above. This product contains sodium metabisulfite, a sulfite that may cause allergic-type reactions, including anaphylactic symptoms and life-threatening or less severe asthmatic episodes, in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people. Serious allergic reactions including anaphylaxis and dermatologic reactions including exfoliative dermatitis, toxic epidermal necrolysis, erythema multiforme, and Stevens-Johnson Syndrome have been reported rarely in patients on tobramycin therapy.

Tobramycin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$27.3M
Medicare Part D spend, 2024
271.0K
Medicare Part D claims, 2024
39
FDA-listed manufacturers (Orange Book)
$6.51
Federal (VA) contract price per pack (5ML)

Frequently asked questions

How much does Tobramycin cost without insurance?
Retail (no-insurance) prices we found for Tobramycin range up to about $5237.05 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $2.99. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Tobramycin?
Yes — our pricing data includes at least one generic listing for Tobramycin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Tobramycin in?
Tobramycin belongs to the aminoglycosides class of antibiotics. WHO classifies it as an 'Watch' antibiotic under its AWaRe stewardship framework.

Learn more about Tobramycin

In-depth answers to common Tobramycin questions, fact-checked against the sources cited in each.

What is the typical cost of Tobramycin Sulfate for uninsured patients?

Without insurance coverage, Tobramycin Sulfate typically costs around $12.73 per 2ml vial (80mg/2ml) at standard retail rates. Uninsured patients can reduce this expense by using prescription discount programs or comparing prices across pharmacies in their area. Since Tobramycin Sulfate is a generic medication, it is generally more affordable than its brand-name equivalents.


Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.