Cefprozil — Compare Prices at US & Canada Pharmacies
Compare real Cefprozil prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.
What is the typical out-of-pocket cost of cefprozil for uninsured patients?
The standard retail price for cefprozil is typically around $86.15, depending on the pharmacy, strength, and quantity dispensed. Uninsured patients can reduce this cost significantly by comparing prices between different pharmacies or looking into prescription discount programs, which may lower the price to between $25 and $35 per prescription.
How does cefprozil pricing change for people with insurance coverage?
Cost-sharing amounts for cefprozil vary by individual insurance plan and may include a copay, coinsurance percentage, or deductible. Patients should verify their plan's coverage details directly with their insurer or pharmacist. In some cases, generic cefprozil may be available at a lower copay than brand-name alternatives, and comparing available options at the pharmacy counter can help identify the most affordable choice.
Is cefprozil covered under Medicare, and what would a patient pay?
Cefprozil is typically covered under Medicare Advantage plans and Medicare Part D prescription drug coverage, though specific copay amounts and coverage rules depend on the individual plan selected. Patients enrolled in these plans should contact their plan administrator or review their coverage documents to confirm cefprozil eligibility and expected out-of-pocket costs.
What brand names is cefprozil sold under, and are generics available?
Cefprozil is sold under the brand name Cefzil, manufactured by Bristol-Myers Squibb. Multiple generic manufacturers produce cefprozil, including Lupin, Apotex, and Aurobindo, among others. Generic versions are bioequivalent to the brand name and typically cost significantly less, making them a cost-effective option for most patients.
Cefprozil prices at US pharmacies
(Cefprozil) — bottle, 100ml of 250mg/5ml, qty 100
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Walmart Neighborhood Market Lowest | $31.54 | $28.54 |
| Walmart Pharmacy | $31.54 | $28.54 |
| CVS Pharmacy | $31.75 | $28.75 |
| Walgreens | $33.60 | $30.60 |
| Kroger Pharmacy | $36.83 | $33.83 |
| Harris Teeter Pharmacy | $36.83 | $33.83 |
| Publix | $51.66 | $48.66 |
Cefprozil prices at Canadian pharmacies
| Strength | Pharmacy | Per pill (USD) | Pack total |
|---|---|---|---|
| 500 mg | CanadianPrescriptionDrugstore.com | $1.96 | $176.00 / 90 |
| 500 mg | CanadianPharmacyAdvantage.com | $2.19 | $219.16 / 100 |
| 500 mg | CanadaPharmacies.com | $2.30 | $229.99 / 100 |
| 500 mg | SPFPharmacy.com | $2.49 | $249.00 / 100 |
| 500 mg | InhalersOnline.com | $2.60 | $259.99 / 100 |
| 500 mg | GoldStarMeds.com | $3.02 | $302.40 |
| 500 mg | 1800RxOnline.com | $3.36 | $336.00 |
Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.
What is Cefprozil used for?
Cefprozil is an oral second-generation cephalosporin used for mild to moderate infections of the sinuses, throat and tonsils, middle ear, skin, and lower respiratory tract, including pneumonia and bronchitis. It's taken as a tablet or oral suspension, typically once or twice a day depending on the infection, and comes with the standard cephalosporin note that only intramuscular penicillin — not cefprozil — has been proven to prevent rheumatic fever after strep throat, even though cefprozil effectively clears the acute infection.
Like other cephalosporins, it shares a chemical backbone with penicillins, and cross-reactivity in people with a documented penicillin allergy is well established, occurring in up to about 10% of that group — worth discussing with a prescriber before starting it if you have a known penicillin allergy.
The WHO AWaRe framework classifies cefprozil as a Watch antibiotic, a category for drugs with more potential to drive antibiotic resistance if overused, which is part of why second- and third-generation cephalosporins are generally reserved for situations where a narrower first-line option like amoxicillin isn't appropriate.
How Cefprozil works
Attacks the bacterial cell wall
Cefprozil blocks the enzymes bacteria need to build and maintain their protective cell wall.
The wall weakens and fails
Without a properly built wall, internal pressure causes the bacterial cell to rupture and die.
Susceptible bacteria clear
As bacterial numbers drop, the immune system finishes clearing the infection.
Typical dosage forms & strengths
| Use | Typical adult dose | Form |
|---|---|---|
| Most common infections (adults) | 250–500 mg every 12–24 hours, depending on infection | Tablet / oral suspension |
General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.
Related & alternative drugs
Commonly used for
Warnings & interactions
This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.
Common, usually mild
- Diarrhea, nausea, abdominal discomfort
- Headache, dizziness
- Unpleasant aftertaste
Serious — seek care promptly
- Signs of an allergic reaction: hives, facial/throat swelling, trouble breathing
- Severe or watery diarrhea (possible C. diff colitis)
- Restlessness or unusual mood changes (uncommon)
Contraindications
CONTRAINDICATIONS Cefprozil is contraindicated in patients with known allergy to the cephalosporin class of antibiotics.
Warnings
WARNINGS BEFORE THERAPY WITH CEFPROZIL IS INSTITUTED, CAREFUL INQUIRY SHOULD BE MADE TO DETERMINE WHETHER THE PATIENT HAS HAD PREVIOUS HYPERSENSITIVITY REACTIONS TO CEFPROZIL, CEPHALOSPORINS, PENICILLINS, OR OTHER DRUGS. IF THIS PRODUCT IS TO BE GIVEN TO PENICILLIN-SENSITIVE PATIENTS, CAUTION SHOULD BE EXERCISED BECAUSE CROSS-SENSITIVITY AMONG ß-LACTAM ANTIBIOTICS HAS BEEN CLEARLY DOCUMENTED AND MAY OCCUR IN UP TO 10% OF PATIENTS WITH A HISTORY OF PENICILLIN ALLERGY. IF AN ALLERGIC REACTION TO CEFPROZIL OCCURS, DISCONTINUE THE DRUG.
Cefprozil, by the numbers
Additional public data points beyond retail pricing — useful context, not a price quote.
Frequently asked questions
How much does Cefprozil cost without insurance?
Is there a generic version of Cefprozil?
What drug class is Cefprozil in?
Learn more about Cefprozil
In-depth answers to common Cefprozil questions, fact-checked against the sources cited in each.
What is cefprozil and how does it work?
Cefprozil is a generic prescription antibiotic belonging to the cephalosporin class of medications. It works by disrupting the bacterial cell wall formation process—similar to how penicillin-based antibiotics function. Once the cell wall is compromised and can no longer remain intact, bacteria cannot maintain cellular structure and ultimately die. Cefprozil treats a variety of bacterial infections, including those affecting the sinuses, throat, tonsils, larynx, skin (including staph and strep infections), middle ear, as well as pneumonia and bronchitis. The medication is available in tablet and oral suspension formulations. Dosage and quantity depend on the specific infection type and severity. Cefprozil is ineffective against viral infections and should only be used when a bacterial infection is confirmed.
What side effects can occur with cefprozil use?
Many people tolerate cefprozil well with no side effects, though some experience mild to moderate adverse reactions. Common side effects include diarrhea, nausea, abdominal discomfort, headache, dizziness, an unpleasant aftertaste, and muscle stiffness. In some patients, cefprozil may trigger mood or mental changes such as restlessness and hyperactivity. Allergic reactions to cefprozil can occur and typically present as hives, rashes, dizziness, or breathing difficulty. Anaphylactic shock—a severe and potentially life-threatening allergic response marked by a sudden drop in blood pressure—is a rare but serious possibility. Seek emergency medical attention immediately if you experience signs of a severe allergic reaction. This list does not include all possible side effects; consult your healthcare provider or pharmacist about potential reactions before starting this medication.
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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.
Angelica Balingit, M.D., Internal Medicine