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Glycopeptides WHO AWaRe: Reserve Prescription only

Dalbavancin (Dalvance) — Compare Prices at US & Canada Pharmacies

Compare real Dalbavancin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Generic name Dalbavancin
Also sold as
Dalvance
Drug class
Glycopeptides
AWaRe category
Reserve
Common forms
IV infusion
Notable feature
Single or two-dose full course
Generic available
Yes
Legal status
Prescription only

How does insurance coverage affect the price of Dalbavancin HCl?

Insurance plans vary widely in their coverage of Dalbavancin HCl, and out-of-pocket costs depend entirely on your specific plan's formulary and copay structure. To learn whether your insurance covers this medication and what your copay would be, contact your insurance provider directly for formulary details. If your insurance does not cover Dalbavancin HCl or your copay is high, pharmacy discount cards can sometimes offer an alternative pricing option. Patients on Medicare or Medicaid should verify coverage with their plan administrator and explore whether discount pricing programs may provide a better rate than their insurance copay.

Dalbavancin prices at US pharmacies

(Dalbavancin Hcl) — solution reconstituted, 500mg, qty 3

PharmacyRetail priceWith discount card
CVS Pharmacy Lowest $1682.79 $1679.79
Walgreens $2056.16 $2053.16
Publix $3152.66 $3149.66
Kroger Pharmacy $4807.20 $4804.20
Harris Teeter Pharmacy $4807.20 $4804.20
Walmart Neighborhood Market $5130.52 $5127.52
Walmart Pharmacy $5130.52 $5127.52

Dalvance (Dalbavancin Hcl) — solution reconstituted, 500mg, qty 3

PharmacyRetail priceWith discount card
CVS Pharmacy Lowest $1682.79 $1679.79
Walgreens $2056.16 $2053.16
Publix $3152.66 $3149.66
Kroger Pharmacy $4807.20 $4804.20
Harris Teeter Pharmacy $4807.20 $4804.20
Walmart Neighborhood Market $5130.52 $5127.52
Walmart Pharmacy $5130.52 $5127.52

Dalbavancin prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Dalbavancin in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Dalbavancin used for?

Dalbavancin is a lipoglycopeptide antibiotic — related to vancomycin — with a standout feature: an extremely long half-life that allows a full course of treatment for acute bacterial skin and skin structure infections with just one or two IV doses, given a week apart, instead of days of repeated infusions. That's a meaningful practical advantage for infections that would otherwise require a prolonged IV line or an extended hospital stay, and it's part of why dalbavancin has become an option for treating serious skin infections in an outpatient setting.

Like vancomycin, dalbavancin is active against gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus), which is a large part of its clinical usefulness. The WHO AWaRe framework classifies it as a Reserve antibiotic, reflecting both its role against resistant organisms and the importance of using newer antibiotics like this one carefully to preserve their long-term effectiveness.

Because dalbavancin stays in the body for weeks after a single dose, there's no quick way to stop its effects once it's given — something to be aware of if a significant allergic reaction or side effect develops. Its FDA label notes minimal known drug-drug interactions, which is an advantage in patients on multiple other medications.

How Dalbavancin works

  1. Attacks the bacterial cell wall

    Like vancomycin, dalbavancin binds to a specific building block bacteria need to construct their cell wall.

  2. Wall construction fails

    Blocking this step prevents susceptible bacteria, including MRSA, from building and repairing their cell wall.

  3. Long-lasting levels keep working

    Its long half-life means a single dose (or two doses a week apart) maintains effective drug levels for the full course of treatment.

Typical dosage forms & strengths

UseTypical adult doseForm
Acute bacterial skin and skin structure infections1500 mg IV as a single dose, or 1000 mg followed by 500 mg one week laterIV infusion

General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Nausea, headache
  • Diarrhea

Serious — seek care promptly

  • Signs of an allergic reaction: rash, hives, facial/throat swelling, trouble breathing
  • Severe or watery diarrhea (possible C. diff colitis)
  • Liver enzyme changes (uncommon)

Contraindications

4 CONTRAINDICATIONS Dalbavancin for injection is contraindicated in patients with known hypersensitivity to dalbavancin. Known hypersensitivity to dalbavancin ( 4 )

Known drug interactions

7 DRUG INTERACTIONS 7.1 Drug-Laboratory Test Interactions Drug-laboratory test interactions have not been reported. Dalbavancin for injection at therapeutic concentrations does not artificially prolong prothrombin time (PT) or activated partial thromboplastin time (aPTT). 7.2 Drug-Drug Interactions No clinical drug-drug interaction studies have been conducted with dalbavancin for injection. There is minimal potential for drug-drug interactions between dalbavancin for injection and cytochrome P450 (CYP450) substrates, inhibitors, or inducers [see C linical P harmacology ( 12.3 )] .

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary There are no adequate and well-controlled studies with dalbavancin for injection use in pregnant women to evaluate for a drug-associated risk of major birth defects, miscarriage or adverse developmental outcomes. No treatment-related malformations or embryo-fetal toxicity were observed in pregnant rats or rabbits at clinically relevant exposures of dalbavancin.

Dalbavancin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$17.9M
Medicare Part D spend, 2024
3.7K
Medicare Part D claims, 2024
6
FDA-listed manufacturers (Orange Book)
$1005.03
Federal (VA) contract price per pack (1)

Frequently asked questions

How much does Dalbavancin cost without insurance?
Retail (no-insurance) prices we found for Dalbavancin range up to about $5130.52 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $1679.79. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Dalbavancin?
Yes — our pricing data includes at least one generic listing for Dalbavancin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Dalbavancin in?
Dalbavancin belongs to the glycopeptides class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Learn more about Dalbavancin

In-depth answers to common Dalbavancin questions, fact-checked against the sources cited in each.

What is the typical cost of Dalbavancin HCl for uninsured patients?

Without insurance coverage, Dalbavancin HCl typically costs around $6,409.40 per 3, 500mg solution reconstituted at standard retail pharmacy prices. Patients without insurance may be able to reduce this cost by using pharmacy discount cards or coupons, which can lower the price significantly. Uninsured individuals should compare pricing across different pharmacies and inquire about available discount programs to find the best rate.

What is the relationship between Dalbavancin HCl and Dalvance?

Dalbavancin HCl is the generic version of the brand-name antibiotic Dalvance. Both medications contain the same active ingredient and are equally effective. The primary difference is cost—generic dalbavancin HCl is substantially less expensive than its brand-name counterpart Dalvance while providing identical therapeutic benefits.


Sources

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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.