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Glycopeptides WHO AWaRe: Reserve

Kimyrsa — Compare Prices at US & Canada Pharmacies

Compare real Kimyrsa prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Glycopeptides
Common forms
Injectable (reconstituted)
Generic available
Brand only

What should I expect to pay for Kimyrsa with insurance?

Your cost for Kimyrsa depends entirely on your specific insurance plan and whether it includes this medication in its formulary. To find your exact copay or coinsurance amount, contact your insurance provider directly. If your plan does not cover Kimyrsa or your out-of-pocket cost is high, you may qualify for discount prescription programs available at most pharmacies. Those enrolled in Medicare or Medicaid should verify coverage with their plan administrator and ask about supplemental savings options if needed.

Is a generic version of Kimyrsa available?

Kimyrsa is a brand-name antibiotic developed by Melinta Therapeutics, and no generic equivalent is currently available in the United States.

Kimyrsa prices at US pharmacies

Kimyrsa — solution reconstituted, 1200mg, qty 1

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $5704.65 $5701.65
Harris Teeter Pharmacy $5704.65 $5701.65
CVS Pharmacy $5929.68 $5926.68
Walgreens $5986.14 $5983.14
Publix $6022.36 $6019.36
Walmart Neighborhood Market $6124.77 $6121.77
Walmart Pharmacy $6124.77 $6121.77
Costco $6159.23 $6156.23

Kimyrsa prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Kimyrsa in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Kimyrsa used for?

Kimyrsa is a glycopeptide antibiotic manufactured by Melinta Therapeutics. The average retail price for Kimyrsa is $12,808.52 per 1,200 mg solution reconstituted. Discount prescription programs and manufacturer savings may help reduce your out-of-pocket cost to approximately $5,701.65 for the same dosage.

Available forms

solution reconstituted

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

4 CONTRAINDICATIONS Use of intravenous unfractionated heparin sodium is contraindicated for 120 hours (5 days) after KIMYRSA administration. ( 4.1 , 5.1 ) Known hypersensitivity to oritavancin products. ( 4.2 , 5.2 ) 4.1 Intravenous Unfractionated Heparin Sodium Use of intravenous unfractionated heparin sodium is contraindicated for 120 hours (5 days) after KIMYRSA administration because the activated partial thromboplastin time (aPTT) test results may remain falsely elevated for up to 120…

Known drug interactions

7 DRUG INTERACTIONS 7.1 Effect of KIMYRSA on CYP Substrates A screening drug-drug interaction study indicated that oritavancin is a nonspecific, weak inhibitor (CYP2C9 and CYP2C19) or inducer (CYP3A4 and CYP2D6) of several CYP isoforms [see Clinical Pharmacology (12.3) ] . A drug-drug interaction study that assessed the interaction potential of a single 1,200 mg dose of oritavancin on the pharmacokinetics of S-warfarin (CYP2C9 probe substrate) showed no effect of oritavancin on S-warfarin C max or AUC.

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary There are no available data on KIMYRSA use in pregnant women to evaluate for a drug- associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes. In animal reproduction studies, no effects on embryo-fetal development or survival were observed in pregnant rats or rabbits treated at the highest doses throughout organogenesis with intravenous oritavancin, at doses equivalent to 25% of the single clinical dose of 1,200 mg (see Data ) .

Kimyrsa, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$0.6M
Medicare Part D spend, 2024
119
Medicare Part D claims, 2024
$3718
Federal (VA) contract price per pack (1)

Frequently asked questions

How much does Kimyrsa cost without insurance?
Retail (no-insurance) prices we found for Kimyrsa range up to about $6159.23 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $5701.65. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Kimyrsa?
We did not find a generic listing for Kimyrsa in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Kimyrsa in?
Kimyrsa belongs to the glycopeptides class of antibiotics. WHO classifies it as an 'Reserve' antibiotic under its AWaRe stewardship framework.

Learn more about Kimyrsa

In-depth answers to common Kimyrsa questions, fact-checked against the sources cited in each.

What is the typical cost of Kimyrsa for uninsured patients?

Without health insurance coverage, Kimyrsa typically costs $12,808.52 per 1,200 mg solution reconstituted at retail pharmacy prices. Uninsured patients may have access to discount prescription cards or manufacturer assistance programs that can lower this cost to around $5,701.65. Those without insurance are encouraged to explore these savings options at their pharmacy or through the drug manufacturer.


Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.