Orbactiv — Compare Prices at US & Canada Pharmacies
Compare real Orbactiv prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.
What is the out-of-pocket cost of Orbactiv without insurance coverage?
The full retail price of Orbactiv typically runs around $4,084.77 per injection. Patients without insurance can explore discount cards, manufacturer assistance programs, or pharmacy price-comparison services to potentially lower this amount. Checking prices at different pharmacies may also reveal savings opportunities.
What should I expect to pay for Orbactiv if I have commercial insurance?
The cost of Orbactiv with commercial insurance varies significantly depending on your specific plan design and coverage tier. Your out-of-pocket responsibility—whether a copay, coinsurance percentage, or deductible—depends on your plan details. Speaking with your insurance company directly or consulting with your pharmacist can clarify your exact cost responsibility. Discount programs may provide additional savings in some cases.
Is Orbactiv covered by Medicare and what would the cost be?
Medicare does not typically provide coverage for Orbactiv. Patients relying on Medicare would generally pay the full cash price of approximately $4,084.77. Some may qualify for manufacturer patient-assistance programs or other financial support options—discussing these possibilities with your healthcare provider or the drug manufacturer is recommended.
Does a generic version of Orbactiv exist?
Orbactiv is a brand-name medication manufactured by The Medicines Company. Currently, no generic equivalent is available on the market.
Orbactiv prices at US pharmacies
Orbactiv — solution reconstituted, 400mg, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Kroger Pharmacy Lowest | $3512.99 | $3509.99 |
| Harris Teeter Pharmacy | $3512.99 | $3509.99 |
| CVS Pharmacy | $3658.91 | $3655.91 |
| Walgreens | $3686.91 | $3683.91 |
| Publix | $3709.68 | $3706.68 |
| Walmart Neighborhood Market | $3771.75 | $3768.75 |
| Walmart Pharmacy | $3771.75 | $3768.75 |
| Costco | $3792.77 | $3789.77 |
Orbactiv prices at Canadian pharmacies
No Canadian pharmacy pricing was found for Orbactiv in our latest data pull.
Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.
What is Orbactiv used for?
Orbactiv is a prescription antibiotic used to treat serious bacterial skin infections. The medication is administered as an injectable solution and is not covered by Medicare. No generic version is currently available. The typical cash price for Orbactiv is approximately $4,084.77 per dose. Discount programs and pharmacy price-comparison tools may help reduce out-of-pocket costs.
Available forms
solution reconstituted
Related & alternative drugs
Warnings & interactions
This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.
Contraindications
4 CONTRAINDICATIONS Use of intravenous unfractionated heparin sodium is contraindicated for 120 hours (5 days) after ORBACTIV administration. ( 4.1 , 5.1 ) Known hypersensitivity to ORBACTIV ( 4.2 , 5.2 ) 4.1 Intravenous Unfractionated Heparin Sodium Use of intravenous unfractionated heparin sodium is contraindicated for 120 hours (5 days) after ORBACTIV administration because the activated partial thromboplastin time (aPTT) test results may remain falsely elevated for up to 120 hours (5 days)…
Known drug interactions
7 DRUG INTERACTIONS 7.1 Effect of ORBACTIV on CYP Substrates A screening drug-drug interaction study indicated that ORBACTIV is a nonspecific, weak inhibitor (CYP2C9 and CYP2C19) or inducer (CYP3A4 and CYP2D6) of several CYP isoforms [see Clinical Pharmacology ( 12.3 )] . A drug drug interaction study that assessed the interaction potential of a single 1200 mg dose of ORBACTIV on the pharmacokinetics of S-warfarin (CYP2C9 probe substrate) showed no effect of ORBACTIV on S-warfarin C max or AUC.
Pregnancy & breastfeeding
8.1 Pregnancy Risk Summary There are no available data on ORBACTIV use in pregnant women to evaluate for a drug- associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes. In animal reproduction studies, no effects on embryo-fetal development or survival were observed in pregnant rats or rabbits treated at the highest doses throughout organogenesis with intravenous oritavancin, at doses equivalent to 25% of the single clinical dose of 1200 mg ( see Data ).
Orbactiv, by the numbers
Additional public data points beyond retail pricing — useful context, not a price quote.
Frequently asked questions
How much does Orbactiv cost without insurance?
Is there a generic version of Orbactiv?
What drug class is Orbactiv in?
Learn more about Orbactiv
In-depth answers to common Orbactiv questions, fact-checked against the sources cited in each.
What is Orbactiv and how does it work?
Orbactiv is an antibiotic medication prescribed to treat serious bacterial infections affecting the skin. The active ingredient, oritavancin, works by inhibiting bacterial growth. This drug is effective only against bacterial infections and will not treat viral conditions such as colds or influenza. A healthcare professional administers Orbactiv as a single intravenous injection delivered over approximately three hours. Your doctor will determine the appropriate dose based on your medical history, current medications, and how your body responds to treatment. If symptoms do not improve after receiving the injection, contact your doctor. The medication can affect the results of certain medical tests for up to five days following administration, so inform any healthcare providers you see during this window that you have received Orbactiv.
What side effects might occur with Orbactiv treatment?
Common side effects associated with Orbactiv include flushing, itching, nausea, and headaches. Report any of these effects to your doctor or pharmacist, particularly if they persist or worsen. Your physician determined that the benefits of this medication outweigh potential risks when prescribing it to you. Most patients taking Orbactiv experience no serious adverse effects. In rare instances, the drug may trigger Clostridium difficile-associated diarrhea, a severe intestinal condition that can develop during treatment or weeks to months afterward. Seek immediate medical attention if you develop ongoing diarrhea, stomach pain, cramping, or notice blood and mucus in your stool. Consult your healthcare provider for a complete discussion of potential side effects, as this summary is not exhaustive.
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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.