Moxifloxacin (Vigamox) — Compare Prices at US & Canada Pharmacies
Compare real Moxifloxacin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.
How much will Moxifloxacin cost if I have insurance?
Your copay for Moxifloxacin depends on your insurance plan's formulary tier, your specific deductible, and the dosage prescribed. Pharmacy discount programs are sometimes cheaper than the copay itself, so it's worth comparing your insurance copay against discount card pricing at your local pharmacy. Speaking with your pharmacist about both options helps identify the most economical choice for your situation.
Is Moxifloxacin covered by Medicare?
Generic Moxifloxacin in tablet or eye drop form is typically included on Medicare Part D and Medicare Advantage prescription drug formularies. Brand-name versions of moxifloxacin-based medications may have limited or no coverage depending on your specific plan. Using pharmacy discount programs can sometimes deliver a lower out-of-pocket cost than your plan's standard copay.
What brand names contain Moxifloxacin?
Moxifloxacin is available as a generic medication in both oral and ophthalmic forms. Vigamox is the brand-name version of moxifloxacin eye drops. Currently, no brand-name oral tablet formulation of moxifloxacin is marketed in the United States.
How can I reduce the cost of my Moxifloxacin prescription?
Moxifloxacin is typically prescribed for short courses of therapy, which can help keep overall costs manageable. Several strategies may lower your expense: pharmacy discount cards and manufacturer coupons can reduce the price at checkout; Harrow Health (the manufacturer of branded Vigamox) may offer patient assistance or copay reduction programs with specific eligibility requirements; Medicare beneficiaries may qualify for the Part D Extra Help program to reduce coinsurance; employer-sponsored flexible spending accounts (FSAs) or health savings accounts (HSAs) can fund prescription costs with pre-tax dollars; comparing prices across different pharmacies often reveals meaningful savings; and your prescriber may have complimentary medication samples available for eligible patients.
Moxifloxacin prices at US pharmacies
(Moxifloxacin Hcl) — solution (quantity in ml), 0.5%, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Walmart Neighborhood Market Lowest | $18.22 | $15.22 |
| Walmart Pharmacy | $18.22 | $15.22 |
| Food Lion | $15.67 | — |
| Costco | $19.99 | — |
| Publix | $22.72 | — |
| CVS Pharmacy | $26.09 | $23.09 |
| Kroger Pharmacy | $27.99 | $24.99 |
| Harris Teeter Pharmacy | $27.99 | $24.99 |
Moxifloxacin Hcl (2X Day) — solution (quantity in ml), 0.5%, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Kroger Pharmacy Lowest | $154.37 | $151.37 |
| Harris Teeter Pharmacy | $154.37 | $151.37 |
| Walgreens | $163.45 | $160.45 |
| Publix | $165.61 | $162.61 |
| Walmart Neighborhood Market | $165.87 | $162.87 |
| Walmart Pharmacy | $165.87 | $162.87 |
| Food Lion | $163.78 | — |
| CVS Pharmacy | $172.87 | $169.87 |
Moxifloxacin Hcl In Nacl — solution (quantity in ml), 400mg/250ml, qty 250
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Kroger Pharmacy Lowest | $49.89 | $46.89 |
| Harris Teeter Pharmacy | $49.89 | $46.89 |
| Walmart Neighborhood Market | $53.71 | $50.71 |
| Walmart Pharmacy | $53.71 | $50.71 |
| Walgreens | $53.84 | $50.84 |
| Publix | $55.37 | $52.37 |
| CVS Pharmacy | $68.95 | $65.95 |
Moxifloxacin Hcl — solution (quantity in ml), 0.5%, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Walmart Neighborhood Market Lowest | $18.22 | $15.22 |
| Walmart Pharmacy | $18.22 | $15.22 |
| Food Lion | $15.67 | — |
| Costco | $19.99 | — |
| Publix | $22.72 | — |
| CVS Pharmacy | $26.09 | $23.09 |
| Kroger Pharmacy | $27.99 | $24.99 |
| Harris Teeter Pharmacy | $27.99 | $24.99 |
Vigamox (Moxifloxacin Hcl) — solution (quantity in ml), 0.5%, qty 3
| Pharmacy | Retail price | With discount card |
|---|---|---|
| Walmart Neighborhood Market Lowest | $18.22 | $15.22 |
| Walmart Pharmacy | $18.22 | $15.22 |
| Food Lion | $15.67 | — |
| Costco | $19.99 | — |
| Publix | $22.72 | — |
| CVS Pharmacy | $26.09 | $23.09 |
| Kroger Pharmacy | $27.99 | $24.99 |
| Harris Teeter Pharmacy | $27.99 | $24.99 |
Moxifloxacin prices at Canadian pharmacies
| Strength | Pharmacy | Per pill (USD) | Pack total |
|---|---|---|---|
| Default | CanadianPharmacyAdvantage.com | $1.19 | $99.85 / 84 |
| Default | CanadaPharmacies.com | $1.32 | $110.99 / 84 |
| Default | CanadianPrescriptionDrugstore.com | $1.54 | $138.75 / 90 |
| Default | CanadianPharmacyAdvantage.com | $2.53 | $17.71 / 7 |
| Default | CanadaPharmacies.com | $4.14 | $28.99 / 7 |
| Default | OffShoreCheapMeds.com | $8.39 | $83.90 / 10 |
| Default | InhalersOnline.com | $8.84 | $795.24 / 90 |
| Default | InhalersOnline.com | $10.92 | $54.58 / 5 |
| Strength | Pharmacy | Per pill (USD) | Pack total |
|---|---|---|---|
| 0.5 % | CanadianPharmacyAdvantage.com | $1.91 | $28.64 |
| 0.5 % | CanadaPharmacies.com | $2.67 | $39.99 |
| 0.5 % | CanadaPharmacyPro.com | $3.16 | $47.46 |
| 0.5 % | CanadianPharmacyAdvantage.com | $3.27 | $16.37 |
| 0.5 % | CanadaPharmacyPro.com | $3.34 | $33.40 |
| 0.5 % | InhalersOnline.com | $3.82 | $57.33 |
| 0.5 % | CanadaPharmacies.com | $5.40 | $26.99 |
| 0.5 % | InhalersOnline.com | $6.23 | $31.17 |
| 0.5 % | InhalersOnline.com | $6.67 | $99.99 |
| 0.5 % | SPFPharmacy.com | $8.37 | $75.36 |
| Strength | Pharmacy | Per pill (USD) | Pack total |
|---|---|---|---|
| 0.5 % | CanadianPharmacyAdvantage.com | $1.91 | $28.64 |
| 0.5 % | CanadaPharmacies.com | $2.67 | $39.99 |
| 0.5 % | CanadaPharmacyPro.com | $3.16 | $47.46 |
| 0.5 % | CanadianPharmacyAdvantage.com | $3.27 | $16.37 |
| 0.5 % | CanadaPharmacyPro.com | $3.34 | $33.40 |
| 0.5 % | InhalersOnline.com | $3.82 | $57.33 |
| 0.5 % | CanadaPharmacies.com | $5.40 | $26.99 |
| 0.5 % | InhalersOnline.com | $6.23 | $31.17 |
| 0.5 % | InhalersOnline.com | $6.67 | $99.99 |
| 0.5 % | SPFPharmacy.com | $8.37 | $75.36 |
| Strength | Pharmacy | Per pill (USD) | Pack total |
|---|---|---|---|
| 400 mg | CanadianPrescriptionDrugstore.com | $1.19 | $107.50 / 90 |
| 400 mg | InhalersOnline.com | $1.39 | $124.74 / 90 |
| 400 mg | SPFPharmacy.com | $1.71 | $154.26 / 90 |
| 400 mg | InhalersOnline.com | $1.84 | $165.57 / 90 |
| 400 mg | GoldStarMeds.com | $2.19 | $218.61 |
| 400 mg | 1800RxOnline.com | $2.43 | $242.90 |
| 400 mg | SPFPharmacy.com | $2.64 | $79.28 / 30 |
| 400 mg | LifeRxPharmacy.com | $2.78 | $250.35 / 90 |
| 400 mg | CanadaPharmacyPro.com | $2.83 | $254.76 / 90 |
| 400 mg | OffShoreCheapMeds.com | $2.99 | $269.19 / 90 |
Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.
What is Moxifloxacin used for?
Moxifloxacin is a fourth-generation fluoroquinolone available in two very different clinical contexts: as an oral tablet or IV infusion for systemic infections — community-acquired pneumonia, complicated intra-abdominal infections, skin infections, and sinusitis — and as an ophthalmic solution (brand Vigamox) for bacterial conjunctivitis. Those two forms carry very different risk profiles, and it matters which one is actually being discussed. The oral and IV forms carry the full fluoroquinolone boxed warning covering tendinitis and tendon rupture, peripheral neuropathy, central nervous system effects, and worsened myasthenia gravis — serious, sometimes irreversible reactions that led the FDA to restrict fluoroquinolones from routine use in uncomplicated infections where safer alternatives exist. The eye drop, by contrast, delivers such a small systemic dose that those boxed warnings don't meaningfully apply — a few drops in the eye isn't comparable to a 400 mg oral tablet reaching the bloodstream.
Systemically, moxifloxacin has one notable pharmacologic quirk: unlike ciprofloxacin or levofloxacin, it isn't renally cleared to the same degree and reaches only low concentrations in the urine, so it's not recommended for urinary tract infections even though it's a fluoroquinolone. It's also more likely than some other fluoroquinolones to prolong the QT interval, so it's generally avoided in patients with a history of QT prolongation, uncorrected electrolyte abnormalities, or concurrent use of other QT-prolonging drugs and Class IA/III antiarrhythmics. Absorption of the oral tablet is significantly reduced by antacids, sucralfate, and multivitamins containing multivalent cations (calcium, magnesium, iron, zinc), so those need to be separated from the dose by several hours.
As an eye drop, moxifloxacin covers the typical bacterial conjunctivitis organisms — Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae — with a short course of drops, usually three times daily for about a week, and local irritation is the main thing patients notice rather than any systemic effect.
How Moxifloxacin works
Blocks bacterial DNA replication
Moxifloxacin inhibits enzymes (DNA gyrase and topoisomerase IV) that bacteria need to copy their DNA, stopping them from multiplying.
Reaches the target tissue
Given orally or IV, it distributes into lung and other tissue for systemic infections; as eye drops, it concentrates directly on the ocular surface with minimal systemic absorption.
The bacterial cell dies
Unable to replicate its DNA, the bacterium dies, and the infection clears as the immune system removes the remaining debris.
Typical dosage forms & strengths
| Use | Typical adult dose | Form |
|---|---|---|
| Community-acquired pneumonia, skin infections, sinusitis (adults) | 400 mg orally or IV once daily | Tablet or IV infusion |
| Bacterial conjunctivitis (adults and children 1+) | 1 drop in the affected eye(s), 3 times daily for 7 days | 0.5% ophthalmic solution |
General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.
Related & alternative drugs
Commonly used for
Warnings & interactions
This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.
Common, usually mild
- Nausea, diarrhea, or upset stomach (oral/IV)
- Headache or dizziness (oral/IV)
- Eye irritation, redness, or discomfort (eye drops)
Serious — seek care promptly
- Tendon pain, swelling, or rupture (oral/IV)
- Numbness, tingling, or weakness (peripheral neuropathy, oral/IV)
- Confusion, hallucinations, or suicidal thoughts (oral/IV)
- Irregular heartbeat (QT prolongation, oral/IV)
- Signs of a severe allergic reaction (any form)
Boxed warning
WARNING: SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS Fluoroquinolones, including moxifloxacin hydrochloride, have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together [see Warnings and Precautions (5.1) ] , including: Tendinitis and tendon rupture [see Warnings and Precautions (5.2) ] Peripheral neuropathy [see Warnings and Precautions (5.3) ] Central nervous system effects [see Warnings and Precautions (5.4) ] Discontinue moxifloxacin hydrochloride immediately and avoid the use of fluoroquinolones, including…
Contraindications
4 CONTRAINDICATIONS Moxifloxacin tablets are contraindicated in persons with a history of hypersensitivity to moxifloxacin or any member of the quinolone class of antibacterials [see Warnings and Precautions (5.8) ] . Known hypersensitivity to moxifloxacin tablets or other quinolones (4, 5.8 )
Notable drug interactions
| Drug / substance | What can happen |
|---|---|
| Antacids, sucralfate, multivitamins with calcium/iron/zinc | Significantly reduce absorption of oral moxifloxacin; separate dosing by several hours |
| Class IA/III antiarrhythmics and other QT-prolonging drugs | Increased risk of dangerous heart rhythm changes; combination avoided |
| Warfarin | Can enhance anticoagulant effect; monitor INR and for bleeding |
Pregnancy & breastfeeding
8.1 Pregnancy Risk Summary There are no available human data establishing a drug associated risk with the use of moxifloxacin. Based on animal studies with moxifloxacin, moxifloxacin hydrochloride may cause fetal harm. Moxifloxacin did not cause fetal malformations when administered to pregnant rats (IV and oral), rabbits (IV), and monkeys (oral) at exposures that were 0.24 to 2.5 times of those at the human clinical dose (400 mg/day moxifloxacin hydrochloride).
Moxifloxacin, by the numbers
Additional public data points beyond retail pricing — useful context, not a price quote.
Frequently asked questions
How much does Moxifloxacin cost without insurance?
Is there a generic version of Moxifloxacin?
What drug class is Moxifloxacin in?
Learn more about Moxifloxacin
In-depth answers to common Moxifloxacin questions, fact-checked against the sources cited in each.
Is Moxifloxacin covered by Medicaid?
Most state Medicaid programs cover generic Moxifloxacin as an antibiotic. Brand-name moxifloxacin eye drops may have restricted coverage in some states, though the generic formulations are usually covered.
What is Moxifloxacin and how does it work?
Moxifloxacin is a fluoroquinolone antibiotic prescribed to combat a broad spectrum of bacterial infections, including pneumonia, skin and soft tissue infections, intra-abdominal infections, plague, and eye infections such as bacterial conjunctivitis. The drug works by disrupting bacterial DNA replication, effectively killing the organisms and halting their reproduction. Depending on the infection site and severity, moxifloxacin may be given orally as a 400 mg tablet once daily, administered intravenously as an injection or infusion, or applied topically as eye drops (one drop in the affected eye three times daily for seven days). Because fluoroquinolones carry potential for serious adverse effects, topical eye drop formulations—which carry the lowest systemic exposure—represent the most common use. Oral and IV forms are reserved for moderate to severe infections when other antibiotics are unsuitable or ineffective.
What are the side effects of Moxifloxacin?
Common side effects of oral or injected moxifloxacin include gastrointestinal disturbances (nausea, stomach upset, diarrhea), headache, dizziness, and visual disturbances such as blurred vision. Some patients report mood and behavioral changes, including anxiety, agitation, and nervousness. When applied as eye drops, local reactions—such as itching, burning, and eye discomfort—are frequent but typically resolve within minutes. Serious adverse effects, though less common, warrant immediate medical attention. These include permanent or disabling damage to tendons and connective tissue, peripheral nerve damage with numbness or tingling in the extremities, severe or persistent diarrhea, renal impairment, significant skin reactions, and aortic damage. Psychiatric side effects can be severe and include depression, hallucinations, memory disturbances, confusion, paranoia, and suicidal ideation. Allergic reactions, while uncommon, can manifest as urticaria, throat irritation, rash, pruritus, and dyspnea. Severe hypersensitivity skin reactions—marked by dark rash, fever, and facial edema—may require hospitalization. Discontinue moxifloxacin immediately and seek emergency care if you experience signs of tendon rupture, serious mental health changes, numbness in your limbs, or any allergic reaction. Consult your doctor or pharmacist for a complete review of potential side effects before starting this medication.
Are there more affordable antibiotic alternatives to Moxifloxacin?
As a generic medication, moxifloxacin is already priced competitively. Other fluoroquinolone eye drops in a similar class—such as ofloxacin and ciprofloxacin—may occasionally be found at lower prices. However, your healthcare provider chooses a specific antibiotic based on the bacterial pathogen, infection severity, and your individual medical history. Discuss cost-effective options with your doctor to determine whether an alternative antibiotic would be appropriate and effective for your condition.
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Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.
Christopher J. Graber, M.D., MPH, FIDSA, Infectious Disease