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Ophthalmic Antibiotics WHO AWaRe: Watch Prescription only

Ofloxacin (Ocuflox) — Compare Prices at US & Canada Pharmacies

Compare real Ofloxacin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Generic name Ofloxacin
Also sold as
Ocuflox
Drug class
Ophthalmic Antibiotics
Generic available
Yes
Legal status
Prescription only

What is the typical out-of-pocket cost for ofloxacin without coverage?

The average retail price for ofloxacin ophthalmic solution (5ml bottles of 0.3%) is approximately $52.33 per fill. Many pharmacies accept manufacturer coupons, discount cards, and online price-comparison tools that can substantially reduce the final cost at checkout. Consult your pharmacist about available discount options and pricing programs to find the lowest available price.

How much will ofloxacin cost if I have insurance?

Your out-of-pocket expense depends entirely on your specific insurance plan's formulary and copay structure. Copays vary widely across plans. Comparing prices using pharmacy discount cards or coupon programs at the time of purchase may occasionally offer a better rate than your insurance copay. Contact your insurance provider or pharmacy to determine your exact copay and explore alternative pricing methods for the best deal.

Is ofloxacin covered under Medicare, and what would I pay?

Medicare Part D and Medicare Advantage plans typically cover ofloxacin as a generic medication. Average Medicare copays generally range up to $18, though your actual copay depends on your specific plan and formulary tier. Compare this amount against cash prices and any available discount programs at your pharmacy to identify the most cost-effective option for your prescription.

What brand names does ofloxacin go by?

Ofloxacin is the generic formulation. Brand-name versions include Floxin and Ocuflox. The medication is manufactured by Dr. Reddy's Laboratories, Larken Laboratories, and Nivagen Pharmaceuticals.

Ofloxacin prices at US pharmacies

Ocuflox (Ofloxacin) — bottle, 5ml, 0.3% (eye) ophth soln, qty 5

PharmacyRetail priceWith discount card
Walmart Neighborhood Market Lowest $10.75 $7.75
Walmart Pharmacy $10.75 $7.75
Kroger Pharmacy $15.99 $12.99
Harris Teeter Pharmacy $15.99 $12.99
Food Lion $17.56
Costco $17.99
Walgreens $21.22 $18.22
CVS Pharmacy $26.58 $23.58

Ofloxacin — bottle, 5ml, 0.3% (eye) ophth soln, qty 5

PharmacyRetail priceWith discount card
Walmart Neighborhood Market Lowest $10.75 $7.75
Walmart Pharmacy $10.75 $7.75
Kroger Pharmacy $15.99 $12.99
Harris Teeter Pharmacy $15.99 $12.99
Food Lion $17.56
Costco $17.99
Walgreens $21.22 $18.22
CVS Pharmacy $26.58 $23.58

Ofloxacin prices at Canadian pharmacies

StrengthPharmacyPer pill (USD)Pack total
Default CanadianPharmacyAdvantage.com $3.50 $52.48
Default CanadaPharmacies.com $4.27 $63.99
Default CanadianPharmacyAdvantage.com $4.65 $23.26
Default SPFPharmacy.com $6.76 $101.34
Default CanadaPharmacies.com $6.80 $33.99
Default InhalersOnline.com $8.67 $129.99
Default SPFPharmacy.com $10.56 $52.82
Default InhalersOnline.com $12.00 $59.99
Default InhalersOnline.com $34.33 $102.99
Default InhalersOnline.com $50.74 $50.74
StrengthPharmacyPer pill (USD)Pack total
200 mg CanadianPharmacyAdvantage.com $0.24 $24.43 / 100
200 mg CanadaPharmacies.com $0.35 $34.99 / 100
200 mg GoldStarMeds.com $0.73 $21.78 / 30
200 mg 1800RxOnline.com $0.81 $24.20 / 30
200 mg LifeRxPharmacy.com $0.86 $77.67 / 90
200 mg OffShoreCheapMeds.com $0.93 $83.52 / 90
200 mg medsengage.com $0.99 $88.74 / 90
200 mg InhalersOnline.com $1.00 $99.99 / 100
200 mg LifeRxPharmacy.com $1.04 $62.14 / 60
200 mg OffShoreCheapMeds.com $1.11 $66.81 / 60
StrengthPharmacyPer pill (USD)Pack total
400 mg LifeRxPharmacy.com $1.06 $95.84 / 90
400 mg OffShoreCheapMeds.com $1.15 $103.05 / 90
400 mg medsengage.com $1.22 $109.49 / 90
400 mg LifeRxPharmacy.com $1.28 $76.67 / 60
400 mg OffShoreCheapMeds.com $1.37 $82.44 / 60
400 mg GoldStarMeds.com $1.38 $41.28 / 30
400 mg medsengage.com $1.46 $87.59 / 60
400 mg 1800RxOnline.com $1.53 $45.87 / 30
400 mg CanadianPharmacyAdvantage.com $1.76 $175.99 / 100
400 mg CanadaPharmacies.com $1.87 $186.99 / 100
StrengthPharmacyPer pill (USD)Pack total
200 mg CanadianPharmacyAdvantage.com $0.24 $24.43 / 100
200 mg CanadaPharmacies.com $0.35 $34.99 / 100
200 mg GoldStarMeds.com $0.73 $21.78 / 30
200 mg 1800RxOnline.com $0.81 $24.20 / 30
200 mg LifeRxPharmacy.com $0.86 $77.67 / 90
200 mg OffShoreCheapMeds.com $0.93 $83.52 / 90
200 mg medsengage.com $0.99 $88.74 / 90
200 mg InhalersOnline.com $1.00 $99.99 / 100
200 mg LifeRxPharmacy.com $1.04 $62.14 / 60
200 mg OffShoreCheapMeds.com $1.11 $66.81 / 60

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Ofloxacin used for?

Ofloxacin is an FDA-approved prescription antibiotic belonging to the quinolone class, prescribed to treat various bacterial infections. The generic medication is marketed under brand names including Floxin and Ocuflox. Uninsured patients typically face retail prices around $52.33 per 5ml bottle of 0.3% ophthalmic solution, though discount programs and pharmacy price comparisons may offer substantially lower out-of-pocket costs. Learn more about ofloxacin's uses, side effects, and pricing options below.

Available forms

bottle

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

CONTRAINDICATIONS Ofloxacin Otic Solution 0.3% is contraindicated in patients with a history of hypersensitivity to ofloxacin, to other quinolones, or to any of the components in this medication.

Warnings

WARNINGS NOT FOR OPHTHALMIC USE. NOT FOR INJECTION. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolones, including ofloxacin. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, angioedema (including laryngeal, pharyngeal or facial edema), airway obstruction, dyspnea, urticaria, and itching. If an allergic reaction to ofloxacin is suspected, stop the drug. Serious acute hypersensitivity reactions may require immediate emergency treatment. Oxygen and airway management, including intubation, should be administered as clinically indicated.

Known drug interactions

Drug Interactions: Specific drug interaction studies have not been conducted with Ofloxacin Otic Solution 0.3%.

Pregnancy & breastfeeding

Pregnancy Teratogenic effects: Ofloxacin has been shown to have an embryocidal effect in rats at a dose of 810 mg/kg/day and in rabbits at 160 mg/kg/day. These dosages resulted in decreased fetal body weights and increased fetal mortality in rats and rabbits, respectively. Minor fetal skeletal variations were reported in rats receiving doses of 810 mg/kg/day.

Ofloxacin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$27.3M
Medicare Part D spend, 2024
1.5M
Medicare Part D claims, 2024
25
FDA-listed manufacturers (Orange Book)
$7.68
Federal (VA) contract price per pack (5ML)

Frequently asked questions

How much does Ofloxacin cost without insurance?
Retail (no-insurance) prices we found for Ofloxacin range up to about $26.58 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $7.75. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Ofloxacin?
Yes — our pricing data includes at least one generic listing for Ofloxacin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Ofloxacin in?
Ofloxacin belongs to the ophthalmic antibiotics class of antibiotics. WHO classifies it as an 'Watch' antibiotic under its AWaRe stewardship framework.

Learn more about Ofloxacin

In-depth answers to common Ofloxacin questions, fact-checked against the sources cited in each.

How is ofloxacin used to treat infections?

Ofloxacin is a quinolone antibiotic deployed against specific bacterial infections across multiple body sites. The medication comes in oral tablet, ophthalmic solution, and otic solution formulations. Ophthalmic drops target bacterial eye infections, while otic drops address outer ear infections caused by bacteria. Tablets are used for skin, prostate, lung, and urinary tract infections including bladder and kidney infections. The drug also treats pelvic inflammatory disease and certain sexually transmitted infections such as chlamydia and gonorrhea. Ofloxacin is reserved for bacterial infections that cannot be adequately managed with safer antibiotic alternatives and is ineffective against viral illnesses like colds and influenza.

What adverse effects are associated with ofloxacin?

Common side effects include diarrhea, nausea, vomiting, dizziness, and headache. Ophthalmic and otic formulations may produce local burning, irritation, or itching at the application site. The drug increases photosensitivity, requiring sun avoidance during treatment. Do not drive or operate machinery if experiencing dizziness or drowsiness. Seek immediate medical attention for severe gastrointestinal symptoms, abdominal pain, anxiety, gum bleeding, black stools, or vision changes. Serious neurological effects—including mood disturbances, nerve damage, memory problems, confusion, paranoia, or suicidal ideation—warrant immediate discontinuation and physician contact. Fluoroquinolones like ofloxacin carry risk of tendon inflammation or rupture; report severe tendon pain or stiffness promptly. Rarely, the drug may damage the aorta, risking life-threatening bleeding; notify your doctor of persistent chest pain without delay. Discuss all potential adverse reactions and precautions with your healthcare provider before beginning treatment.


Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.