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Ophthalmic Antibiotics Prescription only

Azasite — Compare Prices at US & Canada Pharmacies

Compare real Azasite prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Drug class
Ophthalmic Antibiotics (Macrolide)
Common forms
Eye drop (1% solution)
Typical course
7 days
Generic available
Brand only
Legal status
Prescription only

What is the typical cost of AzaSite without insurance coverage?

The standard retail price for AzaSite is approximately $293.27 per 2.5 ml of 1% solution when paying out of pocket. However, actual prices can vary between pharmacies. Using a discount card or coupon program may reduce your cost. It's worth checking multiple pharmacies or using price-comparison tools to find the best available rate in your area.

How much will I pay for AzaSite if I have insurance?

Your out-of-pocket cost depends entirely on your specific insurance plan and its coverage details. Some plans cover AzaSite fully or with a copay, while others may not include it. Contact your insurance provider directly to learn whether AzaSite is covered under your policy and what your coinsurance or copay would be. If your insurance plan does not cover AzaSite or if your copay is high, discount cards or coupons available through various pharmacy programs may offer a lower alternative price at participating pharmacies.

Is a generic version of AzaSite available?

AzaSite is a brand-name medication produced by Thea Pharma, and no generic equivalent is currently available on the market.

Azasite prices at US pharmacies

Azasite — solution (quantity in ml), 1%, qty 2.5

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $222.81 $219.81
Harris Teeter Pharmacy $222.81 $219.81
Publix $237.84 $234.84
Food Lion $235.16 —
Walmart Neighborhood Market $239.35 $236.35
Walmart Pharmacy $239.35 $236.35
Costco $240.18 $237.18
CVS Pharmacy $249.97 $246.97

Azasite prices at Canadian pharmacies

No Canadian pharmacy pricing was found for Azasite in our latest data pull.

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Azasite used for?

AzaSite is a 1% azithromycin eye drop approved by the FDA for bacterial conjunctivitis — the eye infection commonly called pink eye — caused by susceptible bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae. It uses the same active ingredient as oral azithromycin (Zithromax), but the ophthalmic formulation is built on a gel-forming vehicle that keeps the drug in contact with the eye's surface longer than a typical water-based eye drop, which is what allows for a shorter dosing schedule than most other antibiotic eye drops.

The FDA-approved regimen reflects that: one drop in the affected eye twice a day, 8 to 12 hours apart, for the first two days, then one drop once daily for the next five days — a full course lasting one week. Because it's applied directly to the eye, systemic absorption is minimal, so it doesn't carry the same interaction profile as oral azithromycin.

AzaSite treats bacterial conjunctivitis specifically — it won't help viral or allergic conjunctivitis, which are far more common causes of red, irritated eyes. Confirming the cause with a clinician before starting an antibiotic eye drop helps avoid using an antibiotic you don't actually need.

How Azasite works

  1. Stays on the eye's surface

    The gel vehicle keeps azithromycin in contact with the eye longer than a standard drop, extending its effect between doses.

  2. Blocks bacterial protein synthesis

    Azithromycin binds the 50S ribosomal subunit of susceptible bacteria, stopping them from producing the proteins they need to grow.

  3. Infection clears

    With bacterial growth halted, the immune system clears the remaining organisms and the inflammation resolves.

Typical dosage forms & strengths

UseTypical adult doseForm
Bacterial conjunctivitis (adults and children 1 year and older)1 drop in the affected eye(s) twice daily (8–12 hrs apart) for 2 days, then once daily for 5 more daysOphthalmic solution (1%)

General reference dosing from the FDA label — not personalized advice. Your prescribed dose may differ based on your infection, kidney function, age, and weight. Always follow your prescriber's instructions.

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Common, usually mild

  • Eye irritation or a stinging/burning sensation
  • Temporary blurred vision right after application
  • A sticky or gummy feeling in the eye

Serious — seek care promptly

  • Signs of an allergic reaction: eyelid swelling, rash, difficulty breathing
  • Worsening redness, pain, or discharge (may mean the infection isn't responding)

Contraindications

4 CONTRAINDICATIONS Azasite is contraindicated in patients with hypersensitivity to any component of this product. Hypersensitivity ( 4 )

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary Available data from published literature and postmarketing experience over several decades with azithromycin use in pregnant women have not identified any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes ( see Data ). Developmental toxicity studies with azithromycin in rats, mice, and rabbits showed no drug-induced fetal malformations at doses up to 200 mg/kg/day.

Frequently asked questions

How much does Azasite cost without insurance?
Retail (no-insurance) prices we found for Azasite range up to about $249.97 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $219.81. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Azasite?
We did not find a generic listing for Azasite in current US retail pricing data — it may only be sold under a brand name, or a generic may not yet be commercially available. Ask your pharmacist for the latest status.
What drug class is Azasite in?
Azasite belongs to the ophthalmic antibiotics class of antibiotics.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.