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Ophthalmic Antibiotics Prescription only

Besifloxacin (Besivance) — Compare Prices at US & Canada Pharmacies

Compare real Besifloxacin prices at US and Canadian pharmacies, see official FDA uses and warnings, and find generic alternatives.

Generic name Besifloxacin
Also sold as
Besivance
Drug class
Ophthalmic Antibiotics
Generic available
Yes
Legal status
Prescription only

What is the typical cost of Besifloxacin HCl without insurance coverage?

Without insurance, Besifloxacin HCl typically costs around $257.11 per 5ml bottle of 0.6% solution at retail prices. Uninsured patients may be able to reduce this cost by using prescription discount cards or manufacturer coupons, which can lower the out-of-pocket expense. Choosing the generic version of Besifloxacin HCl instead of the brand-name Besivance can result in meaningful savings.

How does insurance coverage affect the price of Besifloxacin HCl?

Insurance coverage and copay amounts for Besifloxacin HCl vary depending on your specific plan and formulary. To find out your exact copay or whether the medication is covered, contact your insurance provider directly. If your plan does not cover Besifloxacin HCl or has a high copay, discount prescription cards may provide an alternative way to lower your cost. This option is available even if you have Medicare or Medicaid, and comparing prices across different payment methods can help you find the lowest price at your pharmacy.

What brand name does Besifloxacin HCl go by?

Besifloxacin HCl is the generic version of Besivance. The generic formulation contains the same active ingredient as the brand-name product but typically costs considerably less. Both versions are used to treat bacterial eye infections, though pricing and insurance coverage may differ between them.

Besifloxacin prices at US pharmacies

Besifloxacin Hcl — bottle, 5ml of 0.6%, qty 5

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $207.26 $204.26
Harris Teeter Pharmacy $207.26 $204.26
Walgreens $218.94 $215.94
Publix $221.43 $218.43
Food Lion $218.94
Walmart Neighborhood Market $222.66 $219.66
Walmart Pharmacy $222.66 $219.66
CVS Pharmacy $233.86 $230.86

Besivance — bottle, 5ml of 0.6%, qty 5

PharmacyRetail priceWith discount card
Kroger Pharmacy Lowest $207.26 $204.26
Harris Teeter Pharmacy $207.26 $204.26
Walgreens $218.94 $215.94
Publix $221.43 $218.43
Food Lion $218.94
Walmart Neighborhood Market $222.66 $219.66
Walmart Pharmacy $222.66 $219.66
CVS Pharmacy $233.86 $230.86

Besifloxacin prices at Canadian pharmacies

StrengthPharmacyPer pill (USD)Pack total
Default medsengage.com $3.73 $55.96
Default LifeRxPharmacy.com $3.77 $56.57
Default medsengage.com $3.94 $39.38
Default LifeRxPharmacy.com $4.19 $20.95
Default CanadaPharmacyPro.com $5.37 $80.62
Default CanadaPharmacyPro.com $5.67 $56.73
StrengthPharmacyPer pill (USD)Pack total
0.6 % CanadianPharmacyAdvantage.com $4.39 $65.85
0.6 % CanadaPharmacies.com $5.07 $75.99
0.6 % CanadianPharmacyAdvantage.com $5.83 $29.16
0.6 % InhalersOnline.com $7.91 $118.59
0.6 % CanadaPharmacies.com $8.00 $39.99
0.6 % SPFPharmacy.com $8.70 $130.56
0.6 % InhalersOnline.com $12.18 $60.92
0.6 % SPFPharmacy.com $13.02 $65.10
0.6 % CanadianPrescriptionDrugstore.com $13.27 $199.00
StrengthPharmacyPer pill (USD)Pack total
0.60 % InhalersOnline.com $7.91 $118.59
0.60 % SPFPharmacy.com $8.70 $130.56
0.60 % InhalersOnline.com $12.18 $60.92
0.60 % SPFPharmacy.com $13.02 $65.10

Canada prices are converted to USD at time of collection and shown per tablet where available. Ordering from Canadian pharmacies is legal for personal use in most cases but subject to FDA/CBSA rules — see US vs Canada, explained.

What is Besifloxacin used for?

Besifloxacin HCl is an ophthalmic antibiotic produced by Bausch & Lomb Americas. The typical retail price for a 5ml bottle of 0.6% solution is approximately $257.11 per unit. Besifloxacin HCl is the generic formulation; Besivance is the brand-name equivalent.

Available forms

bottle

Related & alternative drugs

Warnings & interactions

This is a summary of the official FDA label text, not personalized medical advice. It does not list every possible interaction or side effect. Always tell your prescriber and pharmacist about every medicine and supplement you take.

Contraindications

4 CONTRAINDICATIONS None. None. ( 4 )

Pregnancy & breastfeeding

8.1 Pregnancy Risk Summary There are no available human data for the use of BESIVANCE during pregnancy to inform any drug-associated risks; however, systemic exposure to besifloxacin from ocular administration is low [see Clinical Pharmacology (12.3) ]. Oral administration of besifloxacin to pregnant rats during organogenesis or during the prenatal and postnatal period did not produce adverse embryofetal or offspring effects at clinically relevant systemic exposures [see Data].

Besifloxacin, by the numbers

Additional public data points beyond retail pricing — useful context, not a price quote.

$6.8M
Medicare Part D spend, 2024
30.3K
Medicare Part D claims, 2024
1
FDA-listed manufacturers (Orange Book)
$101.35
Federal (VA) contract price per pack (5ML)

Frequently asked questions

How much does Besifloxacin cost without insurance?
Retail (no-insurance) prices we found for Besifloxacin range up to about $233.86 depending on pharmacy, form, and quantity. With a free pharmacy discount card, the lowest price we found was $204.26. Your actual price depends on the exact strength, quantity, and pharmacy — see the tables above.
Is there a generic version of Besifloxacin?
Yes — our pricing data includes at least one generic listing for Besifloxacin. Generics contain the same active ingredient and are typically the lowest-cost option; check the price tables above for the generic rows specifically.
What drug class is Besifloxacin in?
Besifloxacin belongs to the ophthalmic antibiotics class of antibiotics.

Sources

Page info

Prices last checked 2026-08-21. Reviewed against FDA and DailyMed official sources — see our review process. Not a substitute for professional medical advice.