Azithromycin Over The Counter

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Azithromycin 250 / 500mg

Azithromycin is the last generation antibiotic representing a macrolides group. The drug is very efficient against the overwhelming number of disease-producing microorganisms. Azithromycin decreases the activity of certain cells of disease-producing microbes which develop proteins. Therefore, this antibiotic possesses bactericidal activity.

Azithromycin acts on such pathogens as pyogenic streptococcus, pneumococcus, Staphylococcus aureus, Streptococcus type C, F, and G, epidermal staphylococcus, Legionella, the causative agent of gonorrhea, as well as the causative agent of syphilis, and so on.

What Is Azithromycin Used For?

Azithromycin is used to treat:

  •  infectious diseases of respiratory organs and ENT organs (tonsillitis, pharyngitis, sinusitis, laryngitis; aggravated chronic bronchitis, pneumonia, average otitis);
  • urogenital bacterial infections proceeding without complications (caused by Chlamydia trachomatis or urethritis);
  • infections of soft tissues and infection of the skin (infectious dermatitis, impetigo);
  • scarlet fever;
  • borreliosis in an initial stage;
  • the stomach diseases associated with Helicobacter pylori.

Contraindications

Do not treat newborn babies as well as children with dysfunction of kidneys or a liver with Azithromycin.
Certain kinds of Azithromycin are not allowed for use by patients under sixteen years. Avoid taking the drug in case of individual intolerance to macrolides, at heavy kidneys, and liver disorders.
There is a certain risk of using Azithromycin by pregnant women. Breastfeeding women should avoid taking the drug.
Do not take Azithromycin if you have heart rhythm disturbances.

Side Effects of Azithromycin

The most common side effects of Azithromycin are vision disorders, nausea, vomiting, discomfort in a stomach, diarrhea, a decrease in the concentration of bicarbonates in blood, lymphocytopenia.

Less than 1% of patients who used Azithromycin experienced: vaginal infections, oral candidiasis, leukopenia, vertigo/dizzinesses, syncope, drowsiness, spasms (it was established that other macrolides also provoke spasms), headache, distortion/loss of taste and feeling of smells, violation of the regularity of bowel movement (rare emptying), digestion disorders, anorexia, meteorism, gastritis, increased fatigue; an increase of creatinine and bilirubin in blood; vaginitis, arthralgia, enthesis, and itch.

Less than 0,1% of patients who used Azithromycin experienced: neutrophilia, thrombocytopenia, hemolytic anemia, mental and motor hyperactivity, nervousness, aggression, adynamy, paresthesia, slackness, neurosis, sleep disorders, sleeplessness, tongue discoloration, constipation, hepatitis (including the changed FPP indicators), a Quincke’s disease, interstitial nephrite, photosensitivity, Lyell’s syndrome, exudative erythema, anaphylaxis, candidiasis.

Strong heartbeat, ventricular arrhythmia is also possible in rare cases. It was established that other macrolide antibiotics can cause similar symptoms. It was also reported about cases of arterial hypotension and lengthening of a QT interval.

Side effects that arise with an unspecified frequency: myasthenia gravis, agitation, fulminant hepatitis, insufficiency of liver function, necrotic hepatitis.

In rare instances, macrolides provoke a deterioration of hearing. Some patients who used Azithromycin experienced hearing disorders, had a ring in ears as well as developing deafness.

Most parts of the cases mentioned above was recorded during clinical studies when the drug was used in high doses for a long time. It is specified in reports that the described problems have reversible character.

How To Take Azithromycin?

Take the drug 1 time a day, an hour before or 2 hours after your meals. If you missed the dose, take it as soon as possible. Thus, the following dose of medicine has to be accepted in 24 hours.
In the case of soft tissues diseases, diseases of respiratory bodies and diseases of skin take 500 mg of Azithromycin a day. Keep using the drug for 3 days.

In the case of uncomplicated cervicitis/urethritis take 1000mg of Azithromycin one time.

Azithromycin for chlamydia treatment

Azithromycin is used to treat Chlamydia of lower parts of a urinogenital system. The drug is well tolerated by patients, and, besides, can be used for the treatment of teenagers and during pregnancy.
Azithromycin dosage for chlamydia treatment is 1000mg used 1 time.
If the chlamydial infection affected upper parts of a urogenital path, the treatment is carried out in short courses with long intervals between courses.
Chlamydia treatment course with Azithromycin usually consists of 3 drug intakes. Take 1000mg of Azithromycin 1 time. An interval between receptions is 7 days ( the drug is used on 1, 7, and 14 days of chlamydia treatment).

Azithromycin for Tonsillitis treatment

All antibiotics intended to treat tonsillitis are usually taken for ten days. Azithromycin is an exception to this rule – it is used for 3-5 days.
The other advantage of this drug is that it is well tolerated by patients – much better than antibiotics from the penicillin group (macrolides are considered as the least toxic antibiotics).
Take 500 mg of Azithromycin a day to treat tonsillitis. If you missed the dose, take it as soon as you remember. Take the next dose in 24 hours.

Children from 0.5 to 12 years should take an oral suspension of Azithromycin once a day. The treatment lasts not less than 3 days, the dose is selected individually.
There are a lot of positive reviews of Azithromycin to treat tonsillitis. The health condition of the patient significantly improves in 5-6 hours after the first pill was taken even in case of purulent tonsillitis.

Azithromycin for sinusitis (arthritis)

In the case of sinusitis (arthritis) take Azithromycin according to one of the schemes below:

  • shock dose (Azithromycin 500 mg) in the first days, the following 3 days 500 mg each day;
  • shock dose (Azithromycin 500 mg) and 4 next days 250 mg a day.

Children under 12 years are prescribed with an oral suspension. The dosage is calculated based on the rate of 10 mg of Azithromycin on 1 kg of bodyweight of the child. Give your child an oral suspension 1 time a day.
In certain cases, it is recommended to use 10 mg/kg of Azithromycin for a child, and decrease the dosage to 5mg/kg for the next 4 days. The highest possible dose is 30 mg/kg.

In case of arthritis, Azithromycin is collected in the illness center and suppresses the harmful bacteria, which are the main reason for its development. The drug effectively removes inflammation in nose bosoms.

Azithromycin Overdose

Overdose is followed by strong nausea, vomiting, digestion disorders, a temporary hearing loss.

If you used too much of Azithromycin contact your health care provider or call the ambulance.

Interaction

The use of Azithromycin together with alcoholic drinks and food slows down the digestion of the drug.

You should check the thrombocytes in blood in case of simultaneous treatment with azithromycin and warfarin.

In case of simultaneous use of Azithromycin and Cycloserine, the activity of the last increases.

The activity of Azithromycin amplifies in case of concomitant use with Tetracycline and chloramine.
Avoid using the drug together with heparin.

Precautions

Azithromycin can interact with various drugs. Therefore, tell your doctor about all medications you take at the moment (including over the counter drugs, vitamins, food supplements, herbs, homeopathic medicines, and so forth) before taking Azithromycin.

Do not start taking other drugs together with Azithromycin before consulting with your doctor.

Take Azithromycin strictly according to your doctor’s instructions even if the illness symptoms practically disappeared after several days from the start of treatment. In some cases, symptoms of an illness can disappear before the infection is completely eliminated.

Azithromycin is absolutely inefficient for treatment of viral infections (for example, cold, flu, chickenpox).

If you take the medicine reducing the acidity of a stomach containing aluminum or magnesium together with Azithromycin, do not take them 2 hours prior to and within the first 2 hours after Azithromycin intake. The concomitant use of these drugs and Azithromycin can reduce the efficiency of the last.

Avoid using Azithromycin if you ever had an allergy to this medicine or to other antibiotics from the group of macrolides.

Before taking the drug tell your doctor if you suffer from one of the diseases mentioned below. In this case, the doctor can prescribe you another dose of medicine or can ask you to have some medical tests necessary to provide you with safe treatment.

  • Liver disorders
  • Kidneys disorders
  • Myasthenia gravis
  • Various forms of arrhythmia
  • Syndrome of long QT in your history or history of someone from your family

In certain cases, treatment with antibiotics including Azithromycin can cause dangerous intestinal infection (pseudomembranous colitis) which is accompanied by strong diarrhea. If you experience strong watery or bloody diarrhea after taking Azithromycin – stop using the drug and immediately contact your doctor. Do not take any medicine for diarrhea before consulting with your doctor.

Azithromycin and Alcohol

Azithromycin can cause dizziness and a temporary vision disorder. These side effects can be amplified if you take Azithromycin together with alcoholic beverages. It is strongly recommended to avoid drinking alcoholic beverages, driving a car, or working with potentially dangerous equipment during treatment.

Azithromycin During Pregnancy

Researches on animals showed that Azithromycin is safe for a fetus. There were a lot of clinical studies regarding the influence of Azithromycin on the development of pregnancy in women. which used the drug for the treatment of various infections (for example, chlamydiosis) including during the first trimester of pregnancy. These studies showed that Azithromycin has no negative impact on the baby.

During the research conducted in 2006, 123 women who used Azithromycin on different durations of pregnancy were observed. The results of this research showed that the use of Azithromycin during pregnancy does not increase the risk of the emergence of malformations in the child or other serious side effects.

Nevertheless, using Azithromycin during pregnancy is recommended only under the control of your doctor. Inform your doctor if you are pregnant or plan pregnancy soon before taking the drug. Also, tell your doctor if you become pregnant during the treatment with Azithromycin.

Azithromycin and Breastfeeding

Azithromycin gets into breast milk in quantity much smaller, than the medicine dose allowed for use in the treatment of babies and, most likely, cannot cause serious side effects in babies.

In this regard, it is allowed to use the drug during breastfeeding without the feeding termination.

One research showed that the use of antibiotics from the macrolides group (Azithromycin also belongs to this group) within the first 3 months of the child’s life can increase the risk of narrowing of the pylori department of a stomach. However, there were children observed receiving Erythromycin, and that other studies did not confirm these results.

The use of antibiotics including Azithromycin during breastfeeding can increase a risk candidosis stomatitis, diaper dermatitis and diarrhea development is a child.

The concentration of Azithromycin in breast milk gradually increases with each new dose of the medicine used by a feeding woman. The medicine continues to remain in milk within several days after the reception of the last dose. That is why it is useless to decant milk or to postpone feeding of a child.

Azithromycin Review

The reviews of Azithromycin after treatment of chlamydiosis, tonsillitis, arthritis, frontal sinusitis and other diseases caused by microbes, sensitive to drug, are positive in most cases.
The drug represents a powerful substance to fight against bacterial infection. Moreover, it is well tolerated by patients. The side effects are observed infrequently and completely disappear after the treatment termination.

Azithromycin reviews by doctors are also positive. The main advantages of Azithromycin Z Pak, according to physicians, is that it:

  • possesses anti-inflammatory and immunomodulatory action;
  • is characterized by a high activity concerning probable causative agents of infectious diseases of respiratory bodies;
  • creating a high concentration in tissues shows bactericidal properties against the most harmful bacteria;
  • is effective in case of atypical causative agents which breed in cells (in particular, against mycoplasmas and chlamydia);
  • can be used during pregnancy;
  • has an oral suspension form suitable for children.

The postantibiotic effect of Azithromycin allows us to use it using short courses. Besides, under the influence of drugs even microbes, resistant to it, become more sensitive to the influence of factors of immune protection.
Unlike Erythromycin, which is a basis of macrolides antibiotics, Azithromycin does not decay in the sour environment of a stomach and has a lower impact on gastrointestinal tract motility.

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